“…Using numerical examples, it is shown that the modified benchmark can be reliably estimated using closed-loop operational data, which is vital for the application of this technique in process industries. [146,147], Normalized RGA [39], relative interaction array [154], decomposed relative interaction array [38,40], µ-interaction measure [26,27], ν-gap metric [106] and dissipativity [4,5,149]. Comprehensive reviews on the methods available for IO pairing selection are available in [135][136][137].…”