A new chemiluminescence method for determination of clonazepam and diazepam based on 1-Ethyl-3-Methylimidazolium Ethylsulfate/copper as catalyst

Voltammetric determination of diazepam using a bismuth modified pencil graphite electrode

“…6 So it is necessary to determine 1,4-benzodiazepines in pharmaceutical products and biological uids. Different methods such as liquid chromatography, [7][8][9][10][11][12] spectrophotometry, [13][14][15] capillary electrophoresis, 16 gas chromatography [17][18][19][20] and electrochemical techniques have been used for the determination of DZ in plasma, urine, saliva and drug samples. [21][22][23][24][25][26][27] In non-electrochemical methods, the time of analysis is long and the methods have intrinsic defects such as low sensitivity, expensive devices so require specic pre-treatment prior to the analysis.…”

Electroanalytical determination of diazepam in tablet and human serum samples using a multiwalled carbon nanotube embedded molecularly imprinted polymer-modified carbon paste electrode

“…It is also an abused drug in which sudden withdrawal, particularly from high doses, carries the risk of epileptic seizures. 2 A variety of analytical methods have been developed for the determination of this drug in both pharmaceutical and biological samples, such as spectrophotometry, [3][4][5][6] different chromatographic methods (HPLC, LC/MS, GC, GC/MS, and TLC), [7][8][9][10][11] dispersive liquid-liquid microextraction, 12 capillary electrophoresis, 2 radioimmunoassay 13 and electrochemical methods. [14][15][16][17][18][19] Among these methods, electrochemical techniques are a powerful and versatile analytical technique that offers high sensitivity, accuracy, and precision as well as a large linear dynamic range, with relatively low-cost instrumentation than other methods.…”

Development of Spectrophotometric Method for Estimating Clonazepam in its Pure Form and in Pharmaceutical Tablets

“…formulations including spectrophotometry 6,7,8,9, GC-MS chromatography 10, HPLC 11,12 capillary electrophoresis 13, electrochem-iluminescence sensors 14 , Voltammetry 15 , potentiometry 16,17 . The purpose of this work is to develop a simple, rapid and accurate spectrophotometric method to measure the quantities (CLZ.)…”