2020
DOI: 10.1016/j.patter.2020.100148
|View full text |Cite
|
Sign up to set email alerts
|

A New Era for Space Life Science: International Standards for Space Omics Processing

Abstract: Space agencies have announced plans for human missions to the Moon to prepare for Mars. However, the space environment presents stressors that include radiation, microgravity, and isolation. Understanding how these factors affect biology is crucial for safe and effective crewed space exploration. There is a need to develop countermeasures, to adapt plants and microbes for nutrient sources and bioregenerative life support, and to limit pathogen infection. Scientists across the world are conducting space omics e… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
44
0

Year Published

2020
2020
2025
2025

Publication Types

Select...
6
3
1

Relationship

3
7

Authors

Journals

citations
Cited by 41 publications
(44 citation statements)
references
References 75 publications
0
44
0
Order By: Relevance
“…As an emerging player in microgravity, macrophages play a vital role in microgravity-induced immune system dysfunction. In particular, the advancement of space omics research may add new fuel to the research of space life sciences [ 115 ]. Although current studies suggest that microgravity affects the function of macrophages, more in-depth exploration is still needed to identify its regulatory mechanisms.…”
Section: Discussionmentioning
confidence: 99%
“…As an emerging player in microgravity, macrophages play a vital role in microgravity-induced immune system dysfunction. In particular, the advancement of space omics research may add new fuel to the research of space life sciences [ 115 ]. Although current studies suggest that microgravity affects the function of macrophages, more in-depth exploration is still needed to identify its regulatory mechanisms.…”
Section: Discussionmentioning
confidence: 99%
“…Scarce material, high cost, and extensive logistics are highly limiting factors for space experiments, making the investigation of plant response to the space environment challenging, reinforcing the requirement of better controls and complementary research in ground simulation and reference facilities [ 37 ]. Moreover, there is a growing awareness in the space biology community to define and use the same criteria when describing the spaceflight experiment metadata so the cross-comparisons between the spaceflight experiments can be performed more rigorously [ 38 , 39 ].…”
Section: Introductionmentioning
confidence: 99%
“…This platform has enabled computational analysis of multi-omics data, visualization of results, and integration with descriptive metadata, such as environmental data (e.g., space radiation dosimetry). GeneLab has already supported dozens of published studies, created a global collaboration to develop uniform standards for spaceflight-omics [ 3 ], and resulted in new space biology discoveries [ 4 , 5 ]. However, it has not yet been possible to use NASA GeneLab to combine and compare space and terrestrial data.…”
Section: Introductionmentioning
confidence: 99%