A New Farnesene Derivative and Other Constituents from Senecio Cannabifolius

Abstract

A new farnesene derivative, 7R*,10S*-epoxy-3E,5E-farnesadien-1,2,11-triol, along with eight known compounds was isolated from the aerial parts of Senecio cannabifolius. Their structures were established on the basis of spectroscopic methods.

Jacaranone Derivatives with Antiproliferative Activity from Crepis pulchra and Relevance of This Group of Plant Metabolites

“…Although the best sources of jacaranones are Asteraceae species, certain species of the Acanthaceae [ 3 ], Bignoniaceae [ 1 , 2 , 37 , 38 , 39 , 40 , 41 ], Delesseriaceae [ 42 ], Gesneriaceae [ 43 , 44 ], Oleaceae [ 45 ], and Theaceae [ 4 , 5 ] families were also found to be sources of jacaranones ( Table 2 ). Among Asteraceae species, the genus Senecio is represented by 20 jacaranone derivative-producing plant species [ 36 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 ]. Besides the Bethencourtia [ 8 ], Packera [ 63 ], and Pentacalia [ 6 , 7 ] genera, each is represented by one species.…”

Heterocyclic terpenes: linear furano- and pyrroloterpenoids

“…63 A farnesane derivative 45 has been isolated from the aerial parts of Senecio cannabifolius (Changbai Mountain, Jilin Province, China). 64 The nerolidane sesquiterpene 46 has been isolated from the seeds of Amomum xanthioides (Seoul, Korea). Compound 46 exhibited cytotoxicity against SK-OV-3 and SK-MEL-2 cells at IC 50 values 16.7 and 8.6 mM, respectively, using a SRB bioassay.…”

Rapid chemical characterization and pharmacological mechanism of Fining Granules in the treatment of chronic bronchitis based on UHPLC–Q-exactive orbitrap mass spectrometer and network pharmacology

“…a perennial herb belonging to the Compositae family, is distributed widely in Northeast China, Japan, and Korea. The rhizomes of this plant have been used in traditional medicine for their antitussive and expectorant properties, particularly in treating chronic bronchitis and acute respiratory infections [ [1] , [2] , [3] , [4] , [5] ]. Conventionally, Feining Granules are prepared from the water extracts of the raw plant material.…”