A new finding on the in-vivo crevice corrosion damage in a CoCrMo hip implant

Oskouei, Reza Hashemi; Barati, Mohammad Reza; Farhoudi, Hamidreza; Taylor, Mark; Solomon, Lucian B.

doi:10.1016/j.msec.2017.05.086

Cited by 25 publications

(22 citation statements)

References 35 publications

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“…Co(II) can significantly reduce the movement ability of macrophages and inhibit cell migration by RhoA downregulation and cytoskeleton reorganization, which is still happened by the emergence of ROS [57]. Ni ions gradually accumulated in cells also affect the ability of bone morphogenetic protein (BMP-2) to induce alkaline phosphatase (ALP) formation [58,59]. Some studies have shown that compared with Nitinol, the surface layer rich in Ti or Ta can significantly reduce the formation of ROS and longevity protein free radicals [60].…”

Section: Different Metal Ions Can Induce Cell Damagementioning

confidence: 99%

The progress on physicochemical properties and biocompatibility of tantalum-based metal bone implants

Li¹,

Yao²,

Zhang³

et al. 2020

SN Appl. Sci.

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Repair, reconstruction, and replacement of congenital malformations, either in case of exogenous or iatrogenic tissue and organ defects, requires utilization of a large number of personalized biomaterials. In recent decades, the improvement of people's quality of life and the prolongation of life expectancy have promoted the development of medical and material science. In addition to the traditionally used stainless steel, other materials such as cobalt-chromium alloy, pure titanium, titanium alloy, and the newly alloy materials continue to emerge, such as tantalum-based alloy materials which have been used in clinic, especially the application of porous tantalum trabecular metal in orthopedics. This paper which has provided good preliminary works for the development of tantalum biomaterials with more advantages in the future such as tantalum dental implants summarizes in detail the progress of tantalum materials in physicochemical properties and biocompatibility in recent years. From the comparison of surface passivation films of different metals in different environments, the electrochemical corrosion behavior of tantalum, the release of different metal ions and the damage to cells, it is concluded that tantalum has excellent corrosion resistance. Besides, the excellent biocompatibility of tantalum metals concluded by cytology, molecular biology, protein adsorption experiment, and hematology experiment, as well as regular follow-up observation of patients with porous tantalum trabecular metal in clinic. The excellent corrosion resistance and biocompatibility of the tantalum metal have a very wide prospect in clinical application.

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Section: Different Metal Ions Can Induce Cell Damagementioning

confidence: 99%

The progress on physicochemical properties and biocompatibility of tantalum-based metal bone implants

Li¹,

Yao²,

Zhang³

et al. 2020

SN Appl. Sci.

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“…Hence, the adequate driving force of localized corrosion may increase which can speed up the degradation of the implant material [21]. Titanium alloys spontaneously form a passive oxide layer (mainly TiO 2 ) that, to some extent, can protect these alloys against corrosion because of its thermodynamic stability, chemical inertia, and low solubility in the body fluids [22]. However, severe corrosion can occur when this passive oxide layer is mechanically disrupted.…”

Section: Introductionmentioning

confidence: 99%

On the Corrosion Behaviour of Low Modulus Titanium Alloys for Medical Implant Applications: A Review

Afzali

Ghomashchi

Oskouei

2019

Metals

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The corrosion behaviour of new generation titanium alloys (β-type with low modulus) for medical implant applications is of paramount importance due to their possible detrimental effects in the human body such as release of toxic metal ions and corrosion products. In spite of remarkable advances in improving the mechanical properties and reducing the elastic modulus, limited studies have been done on the electrochemical corrosion behaviour of various types of low modulus titanium alloys including the effect of different beta-stabilizer alloying elements. This development should aim for a good balance between mechanical properties, design features, metallurgical aspects and, importantly, corrosion resistance. In this article, we review several significant factors that can influence the corrosion resistance of new-generation titanium alloys such as fabrication process, body electrolyte properties, mechanical treatments, alloying composition, surface passive layer, and constituent phases. The essential factors and their critical features are discussed. The impact of various amounts of α and β phases in the microstructure, their interactions, and their dissolution rates on the surface passive layer and bulk corrosion behaviour are reviewed and discussed in detail. In addition, the importance of different corrosion types for various medical implant applications is addressed in order to specify the significance of every corrosion phenomenon in medical implants.

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“…Studies have indicated that a mass of harmful metallic ions can be released from a CoCrMo implant, even without mechanical abrasion, which aggravates the cellular responses. 36,37 The reported higher cytotoxic effect of CoCrMo particles than that of Ti particles is also highly related to the enhanced release of proinammatory factors. 38,39 The greater intrinsic inammation-inducing capability of CoCrMo particles can also be attributed to the more aggressive type of cellular responses they evoke compared with that of Ti particles.…”

Section: Discussionmentioning

confidence: 99%

In vivoanalysis of the effects of CoCrMo and Ti particles on inflammatory responses and osteolysis

Peng

et al. 2018

RSC Adv.

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A new finding on the in-vivo crevice corrosion damage in a CoCrMo hip implant

Cited by 25 publications

References 35 publications

The progress on physicochemical properties and biocompatibility of tantalum-based metal bone implants

The progress on physicochemical properties and biocompatibility of tantalum-based metal bone implants

On the Corrosion Behaviour of Low Modulus Titanium Alloys for Medical Implant Applications: A Review

In vivoanalysis of the effects of CoCrMo and Ti particles on inflammatory responses and osteolysis

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