2008
DOI: 10.32947/ajps.v5i1.392
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A New Formulation of 99mTc-Macroagreggated Albumin (MAA) Freeze-dried Kit for Lungs Scintigraphy

Abstract: A new formulation of macro aggregated albumin (MAA) to be labeled with 99mTc was prepared by a simple and fast method. The suspension of macroagreggated albumin was prepared by diluting 0.4ml human serum albumin (200mg/ml) with normal saline (sterilized and pyrogen free) Concentratedhydrochloric acid was added to denature the protein and this step was followed by the addition of tin in the form of stannite . 3.5ml of polyethylene glycol(PEG) (1mg/ml) was also added to act as antiagglomerating agent. The pH was… Show more

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