A New Method for Hepatic Resection and Hemostasis: Absorbable Plaque and Suture

Abstract

Objective: Alveolar echinococcosis (AE) is a rare life-threatening parasitic infection. Computed tomography perfusion (CTP) imaging has the potential to provide both quantitative and qualitative information about the tissue perfusion characteristics. The purpose of this study was the examination of the characteristic features and feasibility of CTP in AE liver lesions.Material and Methods: CTP scanning was performed in 25 patients who had a total of 35 lesions identified as AE of the liver. Blood flow (BF), blood volume (BV), portal venous perfusion (PVP), arterial liver perfusion (ALP), and hepatic perfusion indexes (HPI) were computed for background liver parenchyma and each AE lesion.Results: Significant differences were detected between perfusion values of the AE lesions and background liver tissue. The BV, BF, ALP, and PVP values for all components of the AE liver lesions were significantly lower than the normal liver parenchyma (p<0.01). Conclusions:We suggest that perfusion imaging can be used in AE of the liver. Thus, the quantitative knowledge of perfusion parameters are obtained via CT perfusion imaging.

Polyglutamic Acid‐Based Elastic and Tough Adhesive Patch Promotes Tissue Regeneration through In Situ Macrophage Modulation

“…However, as wound management plays an essential role in numerous medical practices, sutures are insufficient for complex clinical demands, especially for internal organ wounds. For example, sutures and staples may cause additional trauma to surrounding tissue and induce infection in sealing fragile organs such as lung, [ 1 ] liver, [ 1 , 2 ] and spleen. [ 3 ] Also, risks of leakages are high when applying sutures or staples to the closure of perforated tissues that demand very tight sealing, such as traumatized stomach [ 4 ] and bladder.…”

The sword and the knife: a comparison of ancient Egyptian treatment of sword injuries and present day knife trauma.

“…It avoids prolonged exposure of the underlying structures and prevents infection by stopping bacteria from entering the wound. 19 The Edwin Smith Papyrus is not specific about the technique of suturing but, in modern medicine, the suture technique would depend upon the depth of the laceration. Horizontal mattress sutures are suggested by Forsch for closing gaping wounds 20 and so perhaps this may have been most appropriate for closing an incised wound similar to one caused by a khopesh.…”

Chitosan Lactate Particles for Non-Compression Hemostasis on Hepatic Resection

“…However, these methods can damage surrounding tissues and introduces potential pathological problems to the organ. On the other hand, stitches are often not applicable for diffusive liver injury due to the nature of fragile organ texture and rich blood flow [ 9 , 10 ]. To date, bio-compatible materials loaded with hemostasis agents, such as thrombin/gelatin sponge, showed promising results in hemostasis for severe liver bleeding control [ 11 , 12 , 13 ].…”