A new method of near-infrared fluorescence image-guided hepatectomy for patients with hepatolithiasis: a randomized controlled trial

He, Kunshan; Xiao, Hong; Chi, Chongwei; Cai, Chaonong; Wang, Kun; Li, Peiping; Liu, Xialei; Li, Jian; Shan, Hong; Tian, Jie

doi:10.1007/s00464-019-07290-z

Cited by 24 publications

(25 citation statements)

References 29 publications

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“…As a result of advances in surgical techniques, the overall intraoperative transfusion rate was low, with no difference between the groups. Although studies have shown that fluorescence navigation can reduce the incidence of bile leakage and liver abscess after hepatic segmentectomy and lobectomy [12], and minimize the postoperative hospital stay [13,14], this study did not find that ICG fluorescence navigation reduced postoperative complications or the postoperative hospital stay. However, Spearman's rank correlation and stepwise Logistic regression analysis indicated that ICG fluorescence navigation was associated with shorter operative time and less intraoperative blood loss.…”

Section: Discussioncontrasting

confidence: 69%

“…Recent studies have demonstrated the safety and efficiency of ICG fluorescence navigation in laparoscopic hepatectomy [12][13][14][15]. This study also showed that the intraoperative and postoperative indexes of the ICG-FN group were comparable to or even better than those of the non-ICG-FN group.…”

Section: Discussionsupporting

confidence: 66%

“…Its application can also improve the detection rate of liver tumor focus, especially small lesions in an early stage [9][10][11]. Moreover, laparoscopic hepatectomy using ICG fluorescence navigation is associated with less intraoperative blood loss, a lower transfusion rate, less postoperative complications, and reduced hospital stay, as well as a higher R0 resection rate to avoid a positive surgical margin [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

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Indocyanine green fluorescence navigation in laparoscopic hepatectomy: a retrospective single-center study of 120 cases

Liang

Qian

et al. 2020

Surg Today

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Purpose To explore the role of indocyanine green (ICG) fluorescence navigation in laparoscopic hepatectomy and investigate if the timing of its administration influences the intraoperative observation. Methods The subjects of this retrospective study were 120 patients who underwent laparoscopic hepatectomy; divided into an ICG-FN group (n = 57) and a non-ICG-FN group (n = 63). We analyzed the baseline data and operative data. Results There were no remarkable differences in baseline data such as demographic characteristics, lesion-related characteristics, and liver function parameters between the groups. Operative time and intraoperative blood loss were significantly lower in the ICG-FN group. The rate of R0 resection of malignant tumors was comparable in the ICG-FN and non-ICG-FN groups, but the wide surgical margin rate was significantly higher in the ICG-FN group. The administration of ICG 0–3 or 4–7 days preoperatively did not affect the intraoperative fluorescence imaging. Operative time, intraoperative blood loss, and a wide surgical margin correlated with ICG fluorescence navigation. ICG fluorescence navigation helped to minimize intraoperative blood loss and achieve a wide surgical margin. Conclusion ICG fluorescence navigation is safe and efficient in laparoscopic hepatectomy. It helps to achieve a wide surgical margin, which could result in a better prognosis. The administration of ICG 0–3 days preoperatively is acceptable.

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Section: Discussioncontrasting

confidence: 69%

Section: Discussionsupporting

confidence: 66%

Section: Introductionmentioning

confidence: 99%

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Indocyanine green fluorescence navigation in laparoscopic hepatectomy: a retrospective single-center study of 120 cases

Liang

Qian

et al. 2020

Surg Today

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“…In general, the amount of ICG should be reduced if possible to avoid excessive fluorescence staining that makes the boundary between fluorescent and non-fluorescent area become unclear [ 5 ]. In addition, it should be also avoided ICG injecting into the hepatic vein branch and then entering through the systemic circulation, even a small amount of dye, which may stain whole liver and result in staining failure [ 4 , 5 , 12 ]. Even so, at some point, there is often some inevitably fluorescent noise in the hepatic tissues.…”

Section: Discussionmentioning

confidence: 99%

“…Among which indocyanine green (ICG) has gained widespread acceptance in laparoscopic hepatectomy (LH) [ 3 ]. With the retention and accumulation effect of ICG in lesions, real-time fluorescence imaging can yield visualization of the hepatic parenchyma and biliary tract during LH surgery [ 4 , 5 ]. Thus, the ICG fluorescence imaging (ICG-FI) technique might be able to clearly identify hepatic segmental boundaries and the location of tumors, helping operators to timely adjust the surgical approach and accurately dissect the hepatic segments, avoid tumor residue and reduce vessel damage.…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic ultrasound-guided superselective portal vein injection combined with real-time indocyanine green fluorescence imaging and navigation for accurate resection of localized intrahepatic bile duct dilatation: a case report

et al. 2021

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Background Primary intrahepatic bile duct dilatation can be very harmful to patients although it belongs to benign biliary disease. It can occur in any part of the liver, intraoperative laparoscopic ultrasound (LUS) guidance combine with real-time indocyanine green (ICG) fluorescence navigation are the means of choice for accurate surgical resection. Case presentation Herein we reported a 43-year-old female patient presented with repeated right upper abdominal pain and distension for 3 years and aggravated for half a year, without fever and jaundice. A diagnosis of localized bile duct dilatation with lithiasis in segment 4 (S4) was made on the basis of preoperative imaging. Correspondingly, we selected to perform a laparoscopic surgery with LUS guided real time ICG fluorescence imaging (ICG-FI) and navigation to make the operation more simply and accurately, as well as to retain normal tissues in a certain extent. Laparoscopic resection of S4b and partial S4a was successfully performed, without any complications. Conclusion Laparoscopic anatomical surgery for intrahepatic bile duct dilatation is a technically challenging operation. The combined use of preoperative three-dimensional computerized tomography (CT) planning, intraoperative LUS guided super-selection, ICG hepatic segment staining and real-time fluorescence navigation could help surgeons accurately complete the segmentectomy or subsegmentectomy with minimized trauma and maximized liver tissue preservation.

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Essential updates 2020/2021: Current topics of simulation and navigation in hepatectomy

Saito

Shimada

Morine

et al. 2021

Annals of Gastroent Surgery

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Advances in perioperative care and surgical techniques have significantly improved the outcomes of liver resection during the last three decades. Liver surgery has inherent challenges, including difficult anticipation of complex and variable intrahepatic anatomy and the need for cognitive analysis by the surgeon to integrate preoperative imaging information into the operative field. Therefore, simulation and navigation techniques have been developed in this field.In preoperative simulation, three-dimensional (3D) simulation technology was developed in Germany in the early 2000s, 1 and immediately thereafter software based on an original algorithm was developed in Japan. The development of intraoperative navigation techniques may also help surgeons to perform liver resections as planned. Intraoperative navigation began with intraoperative ultrasound (US) in 1980 2 and progressed to virtual hepatectomy (Hx), [3][4][5][6][7] real-time virtual sonography, 8-12 and finally indocyanine green (ICG) fluorescence. [13][14][15][16][17][18][19][20] Thus, intraoperative navigation has gradually evolved during the past 40 y. This biannual review discusses the essential updates to simulation and navigation in Hx that occurred in the 2-y period from 2020 to 2021. | PREOPER ATIVE S IMUL ATIONPreoperative 3D simulation has enabled surgeons to obtain a great deal of information, such as detailed anatomical visualization, the

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A new method of near-infrared fluorescence image-guided hepatectomy for patients with hepatolithiasis: a randomized controlled trial

Cited by 24 publications

References 29 publications

Indocyanine green fluorescence navigation in laparoscopic hepatectomy: a retrospective single-center study of 120 cases

Indocyanine green fluorescence navigation in laparoscopic hepatectomy: a retrospective single-center study of 120 cases

Laparoscopic ultrasound-guided superselective portal vein injection combined with real-time indocyanine green fluorescence imaging and navigation for accurate resection of localized intrahepatic bile duct dilatation: a case report

Essential updates 2020/2021: Current topics of simulation and navigation in hepatectomy

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