“…They are representative signals that contain valuable information to the nature of the disease, which is reflected in the shape of the waveform [16,17,[20][21][22][23]25]. The common characteristics of these bio-signals are that they are non stationary, contaminated with noise, and have large variation in the morphologies of the waveform not only of different patients or patient groups but also within the same patient [17,21,22,25]. Numerous other waveform classifier such as beat classifier, digital filter, linear and non linear methods have been explored previously, all perform well on training data but generalize poorly [21,22,24,25].…”