“…[5][6][7] Meanwhile, it is the thirdmost-abundant essential element in the body, and too-high or too-low concentrations of Cu 2+ in the human body cause many diseases, for example, amyotrophic lateral sclerosis, Alzheimer's disease, Wilson's syndrome and Crohn's disease. [8][9][10][11] On the other hand, inorganic phosphates (H 2 PO 4 À , HPO 4 2À , PO 4 3À , PPi 4À ) are not only relevant to the environmental health of surface water, but also have a variety of biological and medical functions, including adenosine triphosphate (ATP) synthesis, protein phosphorylation and bone mineralization. 12,13 Although inorganic phosphates are ubiquitous in human activities, excess phosphate content in water also causes many problems, affecting human genetic constitution, energy transformation and skeletal development.…”