A New Precipitating Antigen-Antibody System (Pennsylvania Antigen) in Human Serum

Vierucci, A; Blumberg, Baruch S.; London, William T.; Sutnick, Alton I.

doi:10.1016/s0140-6736(68)91920-x

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1969

1974

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Cited by 5 publications

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“…There have been reported several human serum antigens detectable by isoprecipitins; lipoproteins [1,2], Australia antigen [3,8] and Pennsylvania antigen [10]. The antigen detected in this study is not likely to be a lipoprotein because of negative staining reactions with Sudan black.…”

Section: Discussionmentioning

confidence: 51%

An Isoprecipitin Distinguishing Polymorphism of Human Serum α<sub>1</sub> Globulin

Kasukawa¹,

Yoshida²,

Milgrom³

1969

Int Arch Allergy Immunol

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Section: Discussionmentioning

confidence: 51%

An Isoprecipitin Distinguishing Polymorphism of Human Serum α<sub>1</sub> Globulin

Kasukawa¹,

Yoshida²,

Milgrom³

1969

Int Arch Allergy Immunol

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“…A high percentage of D.S. patients have also been found to produce antibodies against a rare serum antigen (Pe antigen) (Vierucci et al 1968).…”

mentioning

confidence: 99%

Precipitating factors against chicken proteins in patients with Down's syndrome

Adinolfí

Gilligan

1970

Clinical Genetics

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Precipitating factors against chicken serum proteins detected by double diffusion in agar gel were observed in 40 % of D.S. patients studied. The precipitating factors were found to be associated with γG globulins. Similar factors were absent in groups of normal children, mentally retarded subjects, and parents and siblings of the D.S. patients. No association was found between the precipitating factors and the presence of Pe antibodies or Au‐SH antigens.

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