A new species of Demodex (Acari: Demodecidae) from the skin of the vibrissal area of the house mouse Mus musculus (Rodentia: Muridae), with data on parasitism

Izdebska, Joanna N.; Rolbiecki, Leszek; Fryderyk, Sławomira

doi:10.11158/saa.21.8.4

Cited by 10 publications

(6 citation statements)

References 12 publications

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“…32,55,67,90 Demodecid mites tend to be host-specific and, of the 6 species of Demodex mites identified in wild Mus musculus, only Demodex musculi has been reported in laboratory mice. 14,32,[37][38][39][40]55,67,90 Although the life cycle of D. musculi has not been characterized, the life cycle of human Demodex mites is estimated as 14.5 d according to in vitro experiments, and all life stages (eggs, larvae, nymphs, and adults) are found within hair follicles and sebaceous glands. 69,92 Although the effect of Demodex mites on the biology of immunocompetent mice has not been studied, treatment may be necessary in select immunodeficient mouse strains that develop clinical disease, or prior to introducing imported mice into established Demodex mite-free colonies.…”

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confidence: 99%

Ivermectin-compounded Feed Compared with Topical Moxidectin–Imidacloprid for Eradication of Demodex musculi in Laboratory Mice

Nashat

Arbona

Lepherd

et al. 2018

j am assoc lab anim sci

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Demodex musculi is a prostigmatid follicular mite that has rarely been reported in laboratory mice. Although prevalence of this species has not been assessed formally, we have found that many imported mouse strains from noncommercial sources harbor Demodex mites. To assess whether an acaricide can be used to eradicate this mite, infested immunocompromised mice were provided ivermectin-compounded (12 ppm) feed without restriction for 8 wk (n = 10), were treated topically with moxidectin and imidacloprid (MI; 3 and 13 mg/kg, respectively) weekly for 8 wk (n = 10), or remained untreated (n = 10). Mice were confirmed to be mite-infested before treatment and were tested after treatment by using fur plucks (FP), deep skin scrapes (DSS), and PCR analysis of fur swabs. In addition, the presence of mites was confirmed through skin biopsies at 2 study endpoints (1 wk [n = 5] and 12 wk [ n = 5] after treatment). Samples collected before treatment and from untreated mice were positive for D. musculi at all time points and by all test modalities. After treatment, all ivermectin-treated animals remained infested, whereas mice treated with MI were repeatedly negative by all test modalities. An additional shortened treatment trial revealed that 4 wk of MI (n = 7) was insufficient to eradicate mites. Neither treatment produced any evidence of adverse effects according to hematology, serum chemistry parameters, behavior, body weight, and histopathology. Of the 70 PCR assays performed in treated mice, 14 were positive when FP+DSS was negative. In 6 cases where PCR results were negative, 5 were positive by FP+DSS and a single sample was positive on skin biopsy. Although PCR analysis has a high detection rate for D. musculi, FP+DSS can further enhance the detection rate. In conclusion, topical MI administered for 8 consecutive weeks can safely eradicate D. musculi from an immunocompromised mouse strain.

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confidence: 99%

Ivermectin-compounded Feed Compared with Topical Moxidectin–Imidacloprid for Eradication of Demodex musculi in Laboratory Mice

Nashat

Arbona

Lepherd

et al. 2018

j am assoc lab anim sci

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“…In many mammal species, one Demodecidae species is usually found in greater numbers than others, inhabiting more limited microhabitats. For instance, in the house mouse Mus musculus , seven specific Demodecidae taxa are known, with the most common and numerous being D. musculi , inhabiting the hairy skin of the body, whereas other demodecid mite species are restricted to narrow microhabitats (e.g., vibrissae follicles, ear canals, tongue) and are rarer and less numerous [ 48 ]. It is likely that the demodecid mite described in the common noctule in the present study may be the predominant species from this group; however, it does not complete the list of potential future discoveries.…”

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confidence: 99%

The Occurrence of Skin Mites from the Demodecidae and Psorergatidae (Acariformes: Prostigmata) Families in Bats, with a Description of a New Species and New Records

Cierocka

Izdebska

Rolbiecki

et al. 2022

Animals

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The bat skin mites from the closely-related Demodecidae and Psorergatidae families occur synhospitally, populating the same host species and perhaps neighboring microhabitats. However, data on their occurrence and parasitism are fragmentary and dispersed. Thus far, 27 Demodecidae and 18 Psorergatidae species have been described, but the coexistence of mites from both families was only demonstrated in six species of bats. This article presents a description of Demodex pusillus sp. nov. from Nyctalus noctula, including a new host record (first observation of demodecid mites in Nyctalus) and a new record concerning the occurrence of Psorergatoides kerivoluae in Plecotus auritus. It also includes an updated global checklist of the occurrence of Demodecidae and Psorergatidae in Chiroptera, including data on their records/distribution and location in their hosts. In both studied families, the mites exhibit preferences, and even topographic specificity, colonizing different microhabitats in the host, including the eye region (e.g., Meibomian glands of the eyes, corneal surface and eyelid vault), wing membranes and hairy skin on the body. Such colonization of separate microhabitats enables different species to co-occur within the same host, while the total number of parasites determines the level of parasite load, with higher levels being associated with the incidence of disease symptoms. It is worth mentioning that Demodex pusillus sp. nov. is the smallest known representative of the Demodecidae family and one of the smallest animals (70–80 micrometers in length).

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“…The skin of the head is also a characteristic location for demodecid mites parasitising the domestic cat Felis catus Linnaeus, 1758, e.g. D. murilegi Izdebska, Rolbiecki et Fryderyk, 2022 was found solely in the region of the lips, nose and chin, whereas D. cati Megnin, 1877 prefers the nasal region, areas of the eyes and auricles ( Izdebska and Rolbiecki, 2013 ; Izdebska et al, 2016 , 2022 ).…”

Section: Discussionmentioning

confidence: 99%

Morphological and ontogenetic characteristics of Miridex putorii (Acariformes: Demodecidae), a new genus and species of skin mite specific to the European polecat Mustela putorius

Izdebska

Rolbiecki

Rehbein

2022

International Journal for Parasitology: Parasites and Wildlife

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A new species of Demodex (Acari: Demodecidae) from the skin of the vibrissal area of the house mouse Mus musculus (Rodentia: Muridae), with data on parasitism

Cited by 10 publications

References 12 publications

Ivermectin-compounded Feed Compared with Topical Moxidectin–Imidacloprid for Eradication of Demodex musculi in Laboratory Mice

Ivermectin-compounded Feed Compared with Topical Moxidectin–Imidacloprid for Eradication of Demodex musculi in Laboratory Mice

The Occurrence of Skin Mites from the Demodecidae and Psorergatidae (Acariformes: Prostigmata) Families in Bats, with a Description of a New Species and New Records

Morphological and ontogenetic characteristics of Miridex putorii (Acariformes: Demodecidae), a new genus and species of skin mite specific to the European polecat Mustela putorius

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