A new tool to evaluate the impact of chronic urticaria on quality of life: chronic urticaria quality of life questionnaire (CU‐Q<sub>2</sub>oL)

Baiardini, Ilaria; Pasquali, M.; Braido, Fulvio; Fumagalli, Federica; Guerra, Laura; Compalati, Enrico; Braga, M.; Lombardi, Carlo; Fassio, Omar; Canonica, Giorgio Walter

doi:10.1111/j.1398-9995.2005.00833.x

Cited by 265 publications

(222 citation statements)

References 19 publications

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“…Quality of life (QoL) index is used to assess the disease activity. Chronic urticaria quality of life questionnaire (CU-Q2oL), is another tool for determining the severity of CSU quality of life impairment which has also been validated to Turkish language by Kocatürk et al 8,9 Visual analogue scale (VAS) and itch severity score (ISS) are also used to determine the disease activity. 10 In the present study UAS was evaluated since guideline proposes this scoring system in the assessment of disease activity.…”

Section: Discussionmentioning

confidence: 99%

Serum C-Reactive Protein, Neutrophil-Lymphocyte Ratio and Uric Acid Levels in Chronic Spontaneous Urticaria

Karabay¹,

Çerman²,

Altunay³

2016

Turkiye Klinikleri J Dermatol

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A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : Recent studies implicate the role of inflammatory responses in chronic spontaneous urticaria (CSU). The purpose of this study was to analyse the levels of neutrophil-lymphocyte ratio (NLR), serum C-reactive protein (CRP) and uric acid levels in CSU patients, and to investigate the relationship between these inflammatory parameters and disease activity. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : A total of 100 people, consisting of 50 chronic urticaria patients and 50 healthy controls, who have no systemic disease, inflammatory, infectious or autoimmune disease, malignancy, were included in the study. R Re es su ul lt ts s: : NLR and serum CRP levels were significantly higher in patients with CSU than in healthy controls (p< 0.001, p< 0.001, respectively). The levels of uric acid did not show a statistically significant difference between CSU patients and controls (p= 0.359). A significant positive correlation was found between NLR and CRP in patients with CSU (p= 0.001, r= 0.442).When CSU patients were evaluated according to disease severity, serum CRP levels were significantly higher in patients with severe CSU than in patients with mild-moderate CSU (p= 0.038). C Co on nc cl lu us si io on n: : Several biomarkers have been studied in systemic diseases to determine the inflammatory process ongoing and the relationship between these markers and disease activity has been investigated. It can be concluded that CRP and NLR can be used to assess the inflammatory status in CSU and may be useful parameters during the follow-up of these patients. It is known that NLR and CRP are diagnostic and prognostic markers of cardiovascular diseases. Elevated values of NLR and CRP may demand caution regarding cardiovascular comorbidities that may accompany chronic urticaria.K Ke ey y W Wo or rd ds s: : C-reactive protein; neutrophils; uric acid; urticaria Ö ÖZ ZE ET T A Am ma aç ç: : Son dönemde yapılan çalışmalarda kronik spontan ürtikerde (KSÜ) inflamatuar yanıtın üzerinde durulmaktadır. Bu çalışmanın amacı KSÜ hastalarında nötrofil-lenfosit oranı (NLO), serum C-reaktif proteini (CRP) ve ürik asid düzeylerini belirlemek ve bu inflamatuar parametreler ile hastalık aktivitesi arasında ilişki olup olmadığını araştırmaktır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Herhangi bir sistemik hastalığı, inflamatuar veya infeksiyöz hastalığı, malignitesi, otoimmün hastalığı olmayan 50 kronik ürtiker hastası ve 50 sağlıklı kontrol olmak üzere toplam 100 kişi çalışmaya dahil edildi. B Bu ul lg gu ul la ar r: : NLO ve CRP düzeyleri KSÜ hastalarında sağlıklı kontrollere göre anlamlı olarak daha yüksekti (p<0,001, p<0,001, sırasıyla). Ürik asid düzeyleri açısından KSÜ hastaları ve sağlıklı kontroller arasında anlamlı bir fark izlenmedi (p=0,359). KSÜ hastalarında NLO ve CRP arasında anlamlı pozitif korelasyon mevcuttu (p=0,001, r=0,442). KSÜ hastaları hastalık şiddetine göre incelendiğinde serum CRP düzeyleri şiddetli KSÜ hastalarında hafif-orta şiddetli KSÜ h...

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Section: Discussionmentioning

confidence: 99%

Serum C-Reactive Protein, Neutrophil-Lymphocyte Ratio and Uric Acid Levels in Chronic Spontaneous Urticaria

Karabay¹,

Çerman²,

Altunay³

2016

Turkiye Klinikleri J Dermatol

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“…We omitted the questions on interferences with physical activities and eating behaviour, difficulties in keeping concentration and feeling nervous. In the original article by Baiardini et al [4], these four questions did not show a statistically significant difference in patients who reported significant diminished symptoms. The questions on eye and lip swelling were combined to form a question on swelling.…”

Section: Data Collection and Measurementsmentioning

confidence: 83%

“…The MMAS-8 has been demonstrated to have good concurrent and predictive validity and function as a screening tool in outpatient settings with different patient groups. The validated chronic urticaria quality of life questionnaire (CU-Q 2 oL) by Baiardini et al [4] with modifications was used to evaluate the impact of CU on QoL (Table 2). We omitted the questions on interferences with physical activities and eating behaviour, difficulties in keeping concentration and feeling nervous.…”

Section: Data Collection and Measurementsmentioning

confidence: 99%

A study of treatment adherence and quality of life among adults with chronic urticaria in Singapore

2016

Journal of the American Academy of Dermatology

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Background: Chronic urticaria is a common skin condition that causes significant impact on patient's quality of life. Objective: The purpose of the study was to assess adherence to therapy and quality of life of patients with chronic urticaria. We also aimed to study the relationship of medication adherence and quality of life of patients with chronic urticaria. Methods: A cross sectional study was conducted with 103 patients from the dermatology clinic of National University Hospital, Singapore. Patients with chronic urticaria were asked to fill out a questionnaire for assessment of adherence to therapy and quality of life. We used the Morisky 8-Item Medication Adherence Scale to categorize adherence as high, medium, low. For assessment of quality of life, we used the validated chronic urticaria quality of life questionnaire (CU-Q 2 oL) by Bairadani et al. Results:The highest median scores for the items measuring quality of life were interference with sleep and pruritus. We also observed that the majority of patients (71.9%) had low adherence to medical therapy. No difference in adherence was noted in patients on once daily medication or more frequent dosing. There was no significant difference in the quality of life among patients with low and medium adherence to therapy. Conclusion: Quality of life of patients with chronic urticaria does not depend on the patients' adherence to medications. Dosing frequency does not affect adherence in our study population. It is also important to recognize the symptoms and issues most affecting quality of life of patients with chronic urticaria, so as to improve overall management.

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“…Среди общих опросников, которые применялись в изучении показателей качества жизни у пациентов с хронической крапивницей, -World Health Organization Quality of Life Assessment-Brief (WHOQOL-BREF) и Medical Outcomes Survey Short Form (SF-36). Но наиболее часто динамику качества жизни у пациентов с хронической крапивницей определяют с помощью специальных опросников Chronic Urticaria Quality of Life Questionnaire (CU-Q2oL) и Dermatology life Quality Index (DLQI) [37][38][39][40], которые переведены на мно-гие языки, даже имеются русскоязычные версии. Опрос-ник CU-Q2oL содержит 23 вопроса, которые объединены в 6 шкал (зуд, припухлость, влияние на качество повсе-дневной жизни, проблемы со сном, ограничения актив-ности, влияние на внешний вид); ответы оцениваются по 5-балльной шкале Ликерта.…”

Section: -е поколение (метаболиты препаратов 2-го поколения)unclassified

Antihistamines in Treatment of Chronic Urticaria. Review of Modern Recommendations

Леонова¹,

Дворников²,

Скрипкина³

et al. 2016

Med. sov.

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A new tool to evaluate the impact of chronic urticaria on quality of life: chronic urticaria quality of life questionnaire (CU‐Q₂oL)

Cited by 265 publications

References 19 publications

Serum C-Reactive Protein, Neutrophil-Lymphocyte Ratio and Uric Acid Levels in Chronic Spontaneous Urticaria

Serum C-Reactive Protein, Neutrophil-Lymphocyte Ratio and Uric Acid Levels in Chronic Spontaneous Urticaria

A study of treatment adherence and quality of life among adults with chronic urticaria in Singapore

Antihistamines in Treatment of Chronic Urticaria. Review of Modern Recommendations

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A new tool to evaluate the impact of chronic urticaria on quality of life: chronic urticaria quality of life questionnaire (CU‐Q2oL)

Cited by 265 publications

References 19 publications

Serum C-Reactive Protein, Neutrophil-Lymphocyte Ratio and Uric Acid Levels in Chronic Spontaneous Urticaria

Serum C-Reactive Protein, Neutrophil-Lymphocyte Ratio and Uric Acid Levels in Chronic Spontaneous Urticaria

A study of treatment adherence and quality of life among adults with chronic urticaria in Singapore

Antihistamines in Treatment of Chronic Urticaria. Review of Modern Recommendations

Contact Info

Product

Resources

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A new tool to evaluate the impact of chronic urticaria on quality of life: chronic urticaria quality of life questionnaire (CU‐Q₂oL)