A new wortmannine derivative from a Tripterygium wilfordii endophytic fungus Talaromyces wortmannii LGT-4

Abstract

A new wortmannine derivative named wortmannine E (1) was isolated from Talaromyces wortmannii LGT-4, an endophytic fungus of Tripterygium wilfordii. Its structure was established by 1D and 2D NMR spectra.

New Pyrrolobenzoxazine Sesquiterpenoid Derivatives from the Fungus Talaromyces trachyspermus

“…Some species are used as biocontrol agents for soil-borne pathogens in the food industry, and for biotechnological and medical purposes [1]. Many classes of secondary metabolites have been reported from Talaromyces including alkaloids [2,3], peptides [2], esters [2,[4][5][6][7][8][9], phenyl derivatives [2,10], polyketides [2,[11][12][13][14][15][16], pyranones [2,17], quinones [2,18], steroids [2,19], and terpenoids [2,18,[20][21][22][23]. They have shown a wide range of bioactive activities such as cytotoxicity against human cancer cell lines [2,6,24], antibacterial [2-5, 8, 9, 14, 23], anti-inflammatory [15,16,20,21], inhibitory activities of several enzymes [6,10,13,17], antioxidative [11], and antiviral [22] properties.…”