A non‐invasive magnetic resonance imaging‐based model predicts portal venous pressure

Zhang, Qian Wen; Wang, Yi; Wang, Jian; Zhao, Hong; Yu, Hong; Liu, Shi Yuan; Zeng, Xin; Chen, Qi; Hu, Zhiyan; Guo, Wen; Fu, Zhi Ren; Ding, Guo Shan; Shi, Xiaoming; Xie, Wei

doi:10.1111/1751-2980.12325

Cited by 8 publications

(8 citation statements)

References 36 publications

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“…SV, PVD and PVCSA are regarded as important indicators of portal hypertension . As expected, our study showed larger SV, PVD and PVCSA in patients with cirrhosis than healthy controls.…”

Section: Discussionsupporting

confidence: 88%

“…SV, PVD and PVCSA are regarded as important indicators of portal hypertension. 28 As expected, our study showed larger SV, PVD and PVCSA in patients with cirrhosis than healthy controls. Compared with TLV, SV normalized by BW, BSA and BMI seemed to be more useful for evaluating liver function and predicting complications in the cirrhotic group.…”

Section: Discussionsupporting

confidence: 88%

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The evaluation of non‐invasive multi‐slice spiral computed tomography‐based indices for the diagnosis and prognosis prediction of liver cirrhosis

Ling

Lei

Zeng

et al. 2017

J of Digest Diseases

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“…SV, PVD and PVCSA are regarded as important indicators of portal hypertension . As expected, our study showed larger SV, PVD and PVCSA in patients with cirrhosis than healthy controls.…”

Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 88%

The evaluation of non‐invasive multi‐slice spiral computed tomography‐based indices for the diagnosis and prognosis prediction of liver cirrhosis

Ling

Lei

Zeng

et al. 2017

J of Digest Diseases

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“…PVD is regarded as an essential indicator of portal hypertension[35]. However, there are limited studies assessing PVCSA, as it is difficult to measure.…”

Section: Discussionmentioning

confidence: 99%

New formula for predicting standard liver volume in Chinese adults

Feng¹,

Wang²,

Hong³

et al. 2017

WJG

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AIMTo obtain a reference range of morphological indices and establish a formula to accurately predict standard liver volume (SLV) in Chinese adults.METHODSComputed tomography (CT)-estimated total liver volume (CTLV) was determined in 369 Chinese adults. Age, sex, body weight, body height, body mass index, and body surface area (BSA) were recorded using CT. Total splenic volume, portal venous diameter (PVD), splenic venous diameter (SVD), and portal venous cross-sectional area (PVCSA) were also measured by CT. Stepwise multiple linear regression analysis was performed to evaluate the impact of each parameter on CTLV and to develop a new SLV formula. The accuracy of the new formula was compared with the existing formulas in a validation group.RESULTSThe average CTLV was 1205.41 ± 257.53 cm3 (range, 593.80-2250.10 cm3). The average of PVD, SVD and PVCSA was 9.34 ± 1.51 mm, 7.40 ± 1.31 mm and 173.22 ± 48.11 mm2, respectively. The CT-estimated splenic volume of healthy adults varied markedly (range, 46.60-2892.30 cm3). Sex, age, body height, body weight, body mass index, and BSA were significantly correlated with CTLV. BSA showed the strongest correlation (r = 0.546, P < 0.001), and was used to establish a new model for calculating SLV: SLV (cm3) = 758.259 × BSA (m2)-124.272 (R2 = 0.299, P < 0.001). This formula also predicted CTLV more accurately than the existing formulas, but overestimated CTLV in elderly subjects > 70 years of age, and underestimated liver volume when CTLV was > 1800 cm3.CONCLUSIONOur new BSA-based formula is more accurate than other formulas in estimating SLV in Chinese adults.

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“…In cirrhotic patients, due to the presence of portal hypertension and increased blood flow, the PVD, SVD and PVCSA values increase. A PVD > 13 mm is an important index to predict portal hypertension [31] . The mean PVD, SVD and PVCSA values in normal Chinese subjects in this study were 8.84 ± 1.55 mm, 5.53 ± 1.28 mm, 98.33 ± 33.08 mm 3 , respectively.…”

Section: Discussionmentioning

confidence: 99%

New formula for predicting standard liver and spleen volumes in Chinese adults

Yang¹,

Zhao²,

Tantai³

et al. 2019

Preprint

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BACKGROUNDThe liver volume and spleen volum are useful index for cirrhosis patients with esphageal varices. But the calculation of the volume is time-consuming and boring. To solve the problem, we successfully established the liver and spleen volume formula using the body surface area. We compared the liver volume formula with other four formulas, which be proved with highest accuracy and lowest error. Until now, except for the new spleen volume formula in the research, there are few reports about it.AIMTo obtain a reference range of morphological indices, and to establish a formula to accurately predict the standard liver and spleen volumes in Chinese adults.METHODSComputed tomography was used to calculate the estimated total liver volume and spleen volume of 305 Chinese adults without any diseases which could influence the volumes of these two organs. Gender, age, body height, body weight, body surface area and body mass index were determined. Correlation analysis and step-wise multiple linear regression analysis were performed to evaluate the impact of each parameter on the liver and spleen volumes, and then a formula to predict the liver and spleen volumes was established. Finally, the results obtained with the new liver volume formula with existing formulas in a validation group were compared.RESULTSThe average liver and spleen volume values were 1043.18 ± 244.60 cm3 and 175.07 ± 88.15 cm3, respectively. Age, body height, body weight, body surface area and body mass index were significantly correlated with liver and spleen volume. Body surface area showed the strongest correlation with liver volume and spleen volume( p<0.005 and p<0.001). Based on these results, new formulas to calculate the standard liver volume and standard spleen volume were established.CONCLUSIONSCompared the new liver volume formula with the existing formula, it is found that the new liver volume is more accurate. And the accuracy of the spleen volume formula is acceptable. Core tip: To solve the problem of time-consuming and boring in calculating the liver and spleen volume, we successfully established the liver and spleen volume formula can be used in Chinese adult. Though there are some reports about the liver volume, but it is different in spleen volume. The liver volume and spleen volume radio is an useful index to predict the esophageal varices and bleeding risk for cirrhosis patients. Only liver volume formula is not enough, the finding of the spleen volume is very meaningful.

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A non‐invasive magnetic resonance imaging‐based model predicts portal venous pressure

Abstract: The MRI-based formula has great potential for detecting portal hypertension. As a non-invasive measurement, it may be clinically accepted for the replacement of invasive modalities after further refinement.

Cited by 8 publications

References 36 publications

The evaluation of non‐invasive multi‐slice spiral computed tomography‐based indices for the diagnosis and prognosis prediction of liver cirrhosis

The evaluation of non‐invasive multi‐slice spiral computed tomography‐based indices for the diagnosis and prognosis prediction of liver cirrhosis

New formula for predicting standard liver volume in Chinese adults

New formula for predicting standard liver and spleen volumes in Chinese adults

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