A non-metallic SERS-based immunoassay founded by light-harvesting effect and strengthened chemical enhancement

Ma, Jiali; Wang, Dong; Xu, Tao; Wei, Guodong; Gu, Chenjie; Jiang, Tao

doi:10.1039/d3an00171g

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Inorganic Semiconductor Sers-active Substrates1

Sers Principle and Mechanism1

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2023

2024

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Cited by 5 publications

(2 citation statements)

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“…Furthermore, the flat and expansive surfaces of the immunosubstrate ensured signal stability, as evidenced by a low RSD of 11.3% from the corresponding SERS mapping. 99…”

Section: Inorganic Semiconductor Sers-active Substratesmentioning

confidence: 99%

Noble metal-free SERS: mechanisms and applications

Jin,

Zhang,

Yang

et al. 2024

Analyst

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“…Furthermore, the flat and expansive surfaces of the immunosubstrate ensured signal stability, as evidenced by a low RSD of 11.3% from the corresponding SERS mapping. 99…”

Section: Inorganic Semiconductor Sers-active Substratesmentioning

confidence: 99%

Noble metal-free SERS: mechanisms and applications

Jin,

Zhang,

Yang

et al. 2024

Analyst

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“…Generally, CM provides weaker enhancement than EM, typically in the field of enhancement factor (EF) at 10 2 -10 4 . [27][28][29] Furthermore, EM and CM coexist, with CM usually contributing a minor portion of the total enhancement. Particularly in semiconductors, the SERS enhancement mechanism frequently emerges from the interplay of various mechanisms, such as molecular resonance, charge-transfer resonance, electromagnetic resonance, and Mie resonance.…”

Section: Sers Principle and Mechanismmentioning

confidence: 99%

Advancements in SERS‐based biological detection and its application and perspectives in pancreatic cancer

Xu,

Xie,

Lin

et al. 2023

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Surface‐enhanced Raman spectroscopy (SERS) has become an essential bio‐detection technique. Due to its high sensitivity, good signal specificity, and resistance to photobleaching, SERS has been widely used in biomedical research fields such as molecular imaging, tumor diagnosis, and drug monitoring. This review focuses on the progress of SERS in biomedical applications. We first introduce the basic principle of SERS and the progress of substrate research. Then, we summarize the latest research progress on SERS in drug monitoring, cell and exosome detection, tumor imaging, and detection platforms combining microfluidic and lateral flow technologies. Subsequently, the applied research of SERS in early diagnosis of pancreatic cancer and drug efficacy monitoring is described. Finally, the future development direction and possible challenges of SERS in tumor diagnosis and treatment are proposed.

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Highly sensitive detection of cationic pollutants on molybdenum carbide (MXene)/Fe2O3/Ag as a SERS substrate

Sakir,

Akgul,

Demir

2023

Materials Today Chemistry

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A non-metallic SERS-based immunoassay founded by light-harvesting effect and strengthened chemical enhancement

Abstract: Owing to its promising biocompatibility and reliable sensitivity, semiconductor-guided surface-enhanced Raman scattering (SERS) technology has aroused widespread concern in clinical immunoassays.

Cited by 5 publications

References 59 publications

Noble metal-free SERS: mechanisms and applications

Noble metal-free SERS: mechanisms and applications

Advancements in SERS‐based biological detection and its application and perspectives in pancreatic cancer

Highly sensitive detection of cationic pollutants on molybdenum carbide (MXene)/Fe2O3/Ag as a SERS substrate

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