A novel antioxidant isolated from young green barley leaves

Osawa, Toshihiko; Katsuzaki, Hirotaka; Hagiwara, Yoshihide; Hagiwara, Hideaki; Shibamoto, Takayuki

doi:10.1021/jf00019a009

Cited by 100 publications

(75 citation statements)

References 9 publications

(12 reference statements)

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“…The max of 270 and 337 nm and the molecular mass of 594 Da, determined by ESI-MS, suggested that it was 2-O-glycosylisovitexin. This substance has already been described in young barley shoots (37).…”

Section: Differential Accumulation Of Fraction a In Response Tosupporting

confidence: 55%

Structural Analyses and Dynamics of Soluble and Cell Wall-bound Phenolics in a Broad Spectrum Resistance to the Powdery Mildew Fungus in Barley

Röpenack¹,

Parr²,

Schulze‐Lefert³

1998

Journal of Biological Chemistry

211

159

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High pressure liquid chromatography profiles of barley leaf epidermal soluble and cell wall-bound phenolics were analyzed in response to challenge with the fungal pathogen Erysiphe graminis f. sp. hordei. Only one soluble phenolic was found to accumulate differentially in a broad spectrum resistance reaction controlled by mlo resistance alleles in comparison to susceptible near isogenic Mlo lines. Structural analysis identified this compound as a novel phenolic conjugate, p-coumaroyl-hydroxyagmatine (p-CHA). p-CHA but not the nonhydroxylated derivative p-coumaroylagmatine exhibited antifungal activity both in vitro and in vivo. The accumulation of p-CHA in epidermal tissue correlated tightly with fungal penetration attempts of attacked host cells. Furthermore, upon penetration, epidermal cell wallbound phenolics became resistant to saponification at sites of attempted fungal ingress (papilla), indicating a change in, or the addition of, different chemical bonding types. The switch in saponification sensitivity occurred at least 2 h earlier in the mlo-incompatible than in the Mlo-compatible interaction. Our results suggest that p-CHA and the speed of papillae compaction play important roles in non-racespecific powdery mildew defense.

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Section: Differential Accumulation Of Fraction a In Response Tosupporting

confidence: 55%

Structural Analyses and Dynamics of Soluble and Cell Wall-bound Phenolics in a Broad Spectrum Resistance to the Powdery Mildew Fungus in Barley

Röpenack¹,

Parr²,

Schulze‐Lefert³

1998

Journal of Biological Chemistry

211

159

View full text Add to dashboard Cite

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“…free radicals may be derived from the polyphenolic component of BL. This phenolic moiety of the structure can donate hydrogen atoms to deleterious oxy radicals and form the less-reactive phenoxyl radicals in the process (22,23).…”

Section: Discussionmentioning

confidence: 99%

Antioxidative and Hypolipidemic Effects of Barley Leaf Essence in a Rabbit Model of Atherosclerosis

Tseng

et al. 2002

Japanese Journal of Pharmacology

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ABSTRACT-The antioxidative and hypolipidemic effects of barley leaf essence (BL) were investigated in a rabbit model of atherosclerosis. Twenty-four New Zealand White male rabbits were assigned randomly into four dietary groups. The normal group was fed regular rabbit chow and the control group was fed a chow containing 0.5% cholesterol and 10% corn oil. The BL group and the probucol group were fed the same diet as the control group plus 1% (w /w) BL or 1% (w /w) probucol, respectively. The plasma levels of total cholesterol, triacylglycerol, lucigenin-chemiluminescence (CL) and luminol-CL were increased in the control group compared to the normal group; and they were decreased in the BL group and the probucol group compared to the control group. The value of T50 of red blood cell hemolysis and the lag phase of lowdensity lipoprotein oxidation increased in the BL group and in the probucol group compared to the controls. Ninety percent of the intimal surface of the thoracic aorta was covered with atherosclerotic lesions in the control group, but only 60% of the surface was covered in the BL group. This 30% inhibition of hyperlipidemic atherosclerosis by BL was associated with a decrease in plasma lipids and an increase in antioxidative abilities (as measured by T50, lag phase and CL). These results suggest that the antioxidant and hypolipidemic effects of BL could be useful in the prevention of cardiovascular disease in which atherosclerosis is important.

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“…Peroxide value (POV) was determined following the procedure described by Sebranek (1978). Conjugated diene hydroperoxide contents were measured according the method described by Osawa et al (1992).…”

Section: Meat Storage Testmentioning

confidence: 99%

Healthy Pork Production through Dietary n6:n3 Ratio Regulation

Yang¹,

Lien²

2015

JAS

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The meat fat fatty acid composition could influent consumer health. Thus, this study was though dietary n-6:n-3 ratio regulation to production healthy pork. The experiment was used eighty LYD pigs that average weight was 66.5 kg (half male and half female) divide into five groups, they are lard group (L), soybean oil group (SO), commercial fish product group (CFP), canola oil group (CO), and 50% fish oil and 50% canola oil group (FCO) with 4 replicates, this experiment was lasted for 90 days. Experimental results indicated that the growth performances was no difference among groups; serum cholesterol, LDL and LDL-C were lower, meanwhile HDL was higher (P < 0.05) in FCO group than in control group. Back fat thickness, pork color, water holding capacity and meat fat content show no difference among groups. TBARS test on pork storage for 15 days in SO group was significantly higher (P < 0.05) than CO group. The n-6:n-3 ratio of back and belly fat in CFP, FCO and CO groups were significantly lower (P < 0.05) than in lard group. Panel evaluation score in SO group was significantly better (P < 0.05) than CO group in flavor, texture, juicy and total acceptance in longissmus muscle, but no difference in belly meat. In conclusion, the pork n-6: n-3 ratio was decreased with CFP, FCO, and CO supplementation, feeding pigs with low n-6:n-3 ratio fat could production healthy pork for consumers.

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A novel antioxidant isolated from young green barley leaves

Cited by 100 publications

References 9 publications

Structural Analyses and Dynamics of Soluble and Cell Wall-bound Phenolics in a Broad Spectrum Resistance to the Powdery Mildew Fungus in Barley

Structural Analyses and Dynamics of Soluble and Cell Wall-bound Phenolics in a Broad Spectrum Resistance to the Powdery Mildew Fungus in Barley

Antioxidative and Hypolipidemic Effects of Barley Leaf Essence in a Rabbit Model of Atherosclerosis

Healthy Pork Production through Dietary n6:n3 Ratio Regulation

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