A novel characteristic of porous titanium oxide implants

Saeki, Takashi; Jimbo, Ryo; Wennerberg, Ann; Suketa, Naoki; Tanaka, Yasuhiro; Atsuta, Mitsuru

doi:10.1111/j.1600-0501.2007.01404.x

Cited by 52 publications

(43 citation statements)

References 18 publications

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“…Anodic oxidized Ti surfaces have been reported to present hydrophilicity [38,39]. It has also been reported that anodic oxidized Ti surfaces have high surface energy [40,41], which is essential for maintaining surface hydrophilicity [42]. This suggests that the enhanced adsorption of fibronectin and reduction of albumin may be a result of surface energy-related hydrophilicity as well as Mg incorporation.…”

Section: Discussionmentioning

confidence: 99%

Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces

Jimbo¹,

Ivarsson²,

Koskela³

et al. 2010

JOMR

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ObjectivesTo observe the early adsorption of extracellular matrix and blood plasma proteins to magnesium-incorporated titanium oxide surfaces, which has shown superior bone response in animal models.Material and MethodsCommercially pure titanium discs were blasted with titanium dioxide (TiO2) particles (control), and for the test group, TiO2 blasted discs were further processed with a micro-arc oxidation method (test). Surface morphology was investigated by scanning electron microscopy, surface topography by optic interferometry, characterization by X-ray photoelectron spectroscopy (XPS), and by X-ray diffraction (XRD) analysis. The adsorption of 3 different proteins (fibronectin, albumin, and collagen type I) was investigated by an immunoblotting technique.ResultsThe test surface showed a porous structure, whereas the control surface showed a typical TiO2 blasted structure. XPS data revealed magnesium-incorporation to the anodic oxide film of the surface. There was no difference in surface roughness between the control and test surfaces. For the protein adsorption test, the amount of albumin was significantly higher on the control surface whereas the amount of fibronectin was significantly higher on the test surface. Although there was no significant difference, the test surface had a tendency to adsorb more collagen type I.ConclusionsThe magnesium-incorporated anodized surface showed significantly higher fibronectin adsorption and lower albumin adsorption than the blasted surface. These results may be one of the reasons for the excellent bone response previously observed in animal studies.

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Section: Discussionmentioning

confidence: 99%

Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces

Jimbo¹,

Ivarsson²,

Koskela³

et al. 2010

JOMR

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“…Using this principle, Wang et al [60] were the first to report on the increased hydrophilicity of crystalline TiO 2 surfaces upon UV irradiation. Indeed, anatase irradiated with UV-A becomes superhydrophilic, as numerous studies have shown since then [52, 61, 62]. Re-hydrophobization is also a well-known phenomenon of photocatalytic TiO 2 once hydrophilized by UV-A irradiation.…”

Section: Experimental and Marketed Dental Implant Surfaces: Wettinmentioning

confidence: 99%

A review on the wettability of dental implant surfaces II: Biological and clinical aspects

Gittens

Scheideler²,

Rupp³

et al. 2014

Acta Biomaterialia

677

475

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Dental and orthopaedic implants have been under continuous advancement to improve their interactions with bone and ensure a successful outcome for patients. Surface characteristics such as surface topography and surface chemistry can serve as design tools to enhance the biological response around the implant, with in vitro, in vivo and clinical studies confirming their effects. However, the comprehensive design of implants to promote early and long-term osseointegration requires a better understanding of the role of surface wettability and the mechanisms by which it affects the surrounding biological environment. This review provides a general overview of the available information about the contact angle values of experimental and of marketed implant surfaces, some of the techniques used to modify surface wettability of implants, and results from in vitro and clinical studies. We aim to expand the current understanding on the role of wettability of metallic implants at their interface with blood and the biological milieu, as well as with bacteria, and hard and soft tissues.

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“…Moreover, this efficient and cost-effective process presents a potential benefit to any commercially available implant surface and has shown positive host-to-implant response when implants were plasma treated immediately prior to placement in the surgical sites [3]. While promising results have been achieved by the atmospheric treatment of endosseous implants prior to placement, it is also of interest to evaluate whether such surface modification is effective over longer periods of time, since the surface may be contaminated when the implant is reexposed to air [14, 28]. Stachowski et al has reported that there is a possibility to maintain the high surface energy state of the titanium implant for at least 30 days, depending on various factors such as storage conditions [29].…”

Section: Introductionmentioning

confidence: 99%

Plasma Treatment Maintains Surface Energy of the Implant Surface and Enhances Osseointegration

Guastaldi

Yoo

Marin

et al. 2013

International Journal of Biomaterials

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The surface energy of the implant surface has an impact on osseointegration. In this study, 2 surfaces: nonwashed resorbable blasting media (NWRBM; control) and Ar-based nonthermal plasma 30 days (Plasma 30 days; experimental), were investigated with a focus on the surface energy. The surface energy was characterized by the Owens-Wendt-Rabel-Kaelble method and the chemistry by X-ray photoelectron spectroscopy (XPS). Five adult beagle dogs received 8 implants (n = 2 per surface, per tibia). After 2 weeks, the animals were euthanized, and half of the implants (n = 20) were removal torqued and the other half were histologically processed (n = 20). The bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated on the histologic sections. The XPS analysis showed peaks of C, Ca, O, and P for the control and experimental surfaces. While no significant difference was observed for BIC parameter (P > 0.75), a higher level for torque (P < 0.02) and BAFO parameter (P < 0.01) was observed for the experimental group. The surface elemental chemistry was modified by the plasma and lasted for 30 days after treatment resulting in improved biomechanical fixation and bone formation at 2 weeks compared to the control group.

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A novel characteristic of porous titanium oxide implants

Abstract: The anodic-oxidized TiUnite implant has inherent photocatalytic activity. UVA illumination increases the surface hydrophilicity of the implant. However, this increase in hydrophilicity does not improve bone apposition to the implant surface at 4 weeks.

Cited by 52 publications

References 18 publications

Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces

Protein Adsorption to Surface Chemistry and Crystal Structure Modification of Titanium Surfaces

A review on the wettability of dental implant surfaces II: Biological and clinical aspects

Plasma Treatment Maintains Surface Energy of the Implant Surface and Enhances Osseointegration

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