At present, earth conductivity is a key factor which influences the calculation accuracy of the correction value of lowfrequency ground-wave propagation time delay. Based on the practically metrical data and academic estimate method of time delay of low-frequency ground-wave propagation, this paper adopt the immune clonal computation method to inverse the earth equivalent conductivity of the propagation path. Contrast Immune Monoclonal Selection Algorithm (IMCSA) and Immune Polyclonal Selection Algorithm (IPCSA) with Genetic Algorithms (GA), the simulation results show that the IPCSA has better stability and higher precision.