A novel conjunction of folate-targeted carbon nanotubes containing protohemin and oridonin-liposome loaded microbubbles for cancer chemo-sonodynamic therapy

Wang, Chuanjin; Wang, Heng-Zhi; Li, Wei

doi:10.1080/1061186x.2019.1591422

Cited by 17 publications

(9 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More importantly, CUR in the liposome-AuNP system was unaffected in eight hours, while free CUR or CUR-Lips without AuNPs decoction showed a certain degradation [109]. Over the past decade, some preparing methods such as solvent injection, ultrasonication, and hydrothermal method have also been developed to prepare NIRN-Lips [89,91,110,111]. Nevertheless, in terms of particle size uniformity and structural stability, NIRN-Lips prepared by the thin film dispersion method still have irreplaceable advantages.…”

Section: Preparation Methods and Encapsulation Strategy Of Nirn-lipsmentioning

confidence: 99%

Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy

et al. 2021

View full text Add to dashboard Cite

Liposomes are attractive carriers for targeted and controlled drug delivery receiving increasing attention in cancer photothermal therapy. However, the field of creating near-infrared nanomaterial-liposome hybrid nanocarriers (NIRN-Lips) is relatively little understood. The hybrid nanocarriers combine the dual superiority of nanomaterials and liposomes, with more stable particles, enhanced photoluminescence, higher tumor permeability, better tumor-targeted drug delivery, stimulus-responsive drug release, and thus exhibiting better anti-tumor efficacy. Herein, this review covers the liposomes supported various types of near-infrared nanomaterials, including gold-based nanomaterials, carbon-based nanomaterials, and semiconductor quantum dots. Specifically, the NIRN-Lips are described in terms of their feature, synthesis, and drug-release mechanism. The design considerations of NIRN-Lips are highlighted. Further, we briefly introduced the photothermal conversion mechanism of NIRNs and the cell death mechanism induced by photothermal therapy. Subsequently, we provided a brief conclusion of NIRNs-Lips applied in cancer photothermal therapy. Finally, we discussed a synopsis of associated challenges and future perspectives for the applications of NIRN-Lips in cancer photothermal therapy.

show abstract

Section: Preparation Methods and Encapsulation Strategy Of Nirn-lipsmentioning

confidence: 99%

Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy

et al. 2021

View full text Add to dashboard Cite

show abstract

“…The CNT hybrid DDS exhibited significantly higher growth inhibition rates (95.4 ± 5.9%) than liposomal DDS (42.3 ± 2.9%) in vitro, showcasing enhanced therapeutic efficacy. [ 83 ] Moreover, many researchers have studied (in vivo and in vitro studies) and proved that the CNTs could efficiently deliver a range of medicinal and pharmaceutical drugs, such as antiviral drugs, anti‐bacterial drugs, anti‐fungal drugs, anti‐leishmaniasis drugs, anti‐cancer drugs, neurological drugs, antioxidants, anti‐inflammatory drugs, anti‐hypertensive drugs, wound‐healing drugs, immuno‐suppressant drugs, immune‐stimulatory drug, immune‐adjuvant drugs, anti‐hemorrhagic drug, anti‐protozoan drugs, antigenic proteins, and so on. The most popular medications delivered concerning types of CNTs; listed in Figure .…”

Section: Cnt Functionalization and Cnt‐hms Synthesismentioning

confidence: 99%

Carbon Nanotube Hybrid Materials: Efficient and Pertinent Platforms for Antifungal Drug Delivery

Chandra,

Reis,

Kundu

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

Carbon nanotubes (CNTs) have emerged as the brightest nascent artifact to deliver antifungal drugs in drug delivery applications, health care, and pharmaceutical industries. Excellent physio‐chemical features such as huge surface area, tunable side wall, and microneedle‐like morphology make CNTs suitable for drug carriers. Chemical attachments (covalent and non‐covalent functionalization) result in the formation of functionalized CNTs (F‐CNTs) and CNT‐based hybrid materials (CNT‐HMs). These F‐CNTs and CNT‐HMs have substantial antifungal activity and also have the potential to immobilize antifungal drugs such as amphotericin B, nystatin, curcumin, etc. on the exterior or interior surface, securely transport to the target sites, permeate through bio‐barriers, and release these drugs in a controlled manner. As antifungal drug carriers, F‐CNT and CNT‐HMs exhibit more excellent antifungal activity than other conventional drug delivery systems and have the potency to invade biofilm to circumvent the multidrug resistance of fungal species. This review focuses on CNTs and CNT‐HMs for antifungal drug delivery, including their functionalization methods, drug loading approaches, drug release mechanism, cellular internalization, delivery efficiency, and cellular toxicities with their workaround.

show abstract

“…At the same time, metalloporphyrin MBs, which have both CEUS and MRI imaging capabilities, have been developed. 65,66 Chen and co-workers developed MnP-MBs, a type of nanoparticles that can be converted by ultrasound at the tumor site to achieve rapid tumor MRI contrast enhancement. 65 Only a low Mn injection dosage can produce excellent MRI images within 30 min.…”

Section: Applications Of Metalloporphyrin Compounds In Sdtmentioning

confidence: 99%

Application of metalloporphyrin sensitizers for the treatment or diagnosis of tumors

Luo

Wang

Chen

et al. 2022

Journal of Chemical Research

View full text Add to dashboard Cite

At present, metalloporphyrin compounds demonstrate three main uses as anticancer sensitizers: (1) photosensitizers, (2) photothermal conversion agents, and (3) ultrasound sensitizers. Developing efficient sensitizers for cancer with excellent controllability and biocompatibility is an important goal of oncology medicine. Because of the different structural diversity of anticancer sensitizers, such sensitizers are used for treating cancers by employing a variety of tumor treatment methods such as mature photodynamic therapy, commonly used clinically photothermal therapy and promising sonodynamic therapy. Among the many sensitizers, metalloporphyrin-complex sensitizers attract wide attention due to their excellent performance in tumor treatment and diagnosis. This review briefly describes some metalloporphyrin anticancer drugs and diagnostic agents related to photodynamic, photothermal and sonodynamic therapy, and discusses the roles of metal atoms in these drugs.

show abstract

A novel conjunction of folate-targeted carbon nanotubes containing protohemin and oridonin-liposome loaded microbubbles for cancer chemo-sonodynamic therapy

Cited by 17 publications

References 28 publications

Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy

Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy

Carbon Nanotube Hybrid Materials: Efficient and Pertinent Platforms for Antifungal Drug Delivery

Application of metalloporphyrin sensitizers for the treatment or diagnosis of tumors

Contact Info

Product

Resources

About