2022
DOI: 10.1039/d2ra01307j
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A novel construct of an electrochemical acetylcholinesterase biosensor for the investigation of malathion sensitivity to three different insect species using a NiCr2O4/g-C3N4 composite integrated pencil graphite electrode

Abstract: An innovative electrochemical assay has been established to determine pesticide sensitivity against acetylcholinesterase and possible toxicity against insects. The analytical efficiency of three common insect AChEs was determined through this method.

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Cited by 6 publications
(1 citation statement)
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“…The bioconcentration factor values for some fish species have been reported (Howard, 1991;Deka and Mahanta, 2016). Upon entering an organism's body, malathion binds to acetylcholinesterase enzyme (AChE) at the end of the nerve system, thus over-stimulating the nervous system (Bilal et al, 2022). Reduction of antioxidant defense capacity due to oxidative stress and increase in lipid peroxidation (Abdel-Salam et al, 2016) are other proposed mechanisms for malathion toxicity.…”
mentioning
confidence: 99%
“…The bioconcentration factor values for some fish species have been reported (Howard, 1991;Deka and Mahanta, 2016). Upon entering an organism's body, malathion binds to acetylcholinesterase enzyme (AChE) at the end of the nerve system, thus over-stimulating the nervous system (Bilal et al, 2022). Reduction of antioxidant defense capacity due to oxidative stress and increase in lipid peroxidation (Abdel-Salam et al, 2016) are other proposed mechanisms for malathion toxicity.…”
mentioning
confidence: 99%