A novel dairy product fermented with Propionibacterium freudenreichii improves the riboflavin status of deficient rats

Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria

“…Moreover, roseoflavin has been used to obtain constitutive riboflavin overproducing strains of B. subtilis [59], Lactococcus lactis [60], L. plantarum [41], L. fermentum [61] Leuconostoc mesenteroides and Propionibacterium freudenreichii [62–65]. Some of these have been shown to provide beneficial effects in vitamin depleted animals and could be inserted as novel starter cultures [66–69]. …”

Dairy Propionibacteria: Less Conventional Probiotics to Improve the Human and Animal Health

“…As such, vitamin B2 is required for a wide variety of cellular reactions and is involved in vital metabolic processes in the body. It has been reported that P. freudenreichii NIZO2336, a mutant strain that produces larger amounts of riboflavin than the parental strain, improved riboflavin content of yogurt and riboflavin status of rats fed with this product [106].…”

Milk fermented with selected strains of lactic acid bacteria is able to improve folate status of deficient rodents and also prevent folate deficiency

“…Therefore, fermented foods bio-enriched with "natural" or "bio-produced" folates constitute a promising alternative for people to reach the recommended daily 10 9 cell/L 10 9 cell/L 10 9 cell/L 10 12 cell/L g/L % fL pg g/L 10 9 /L FC Dp 6.0 ± 0. intakes through the ingestion of foods that normally form part of their diets. Similar vitamin bio-enrichment strategies using lactic acid bacteria have been previously described by others (Burgess, Smid, & van Sinderen, 2009;Capozzi et al, 2011;Capozzi, Russo, Dueñas, López, & Spano, 2012;LeBlanc et al, 2006); however, the biological activity of the produced vitamins was not evaluated, except for one study where a vitamin B12 strain was used to ferment soymilk and evaluated in an animal model (Molina, Médici, Font de Valdez, & Taranto, 2012). The present study was conducted to evaluate the effectiveness of a novel fermented milk, manufactured with folateproducing lactic acid bacteria in a folate depletion/repletion mouse model and also in a folate prevention model.…”