A novel method for coating calcium phosphate with trace elements extracted from bone using electrical stimulation

OTA, Fuki; Fujisaki, Kazuhiro; Osanai, Keita; Sasagawa, Kazuhiko

doi:10.1016/j.jmbbm.2022.105330

Cited by 2 publications

(2 citation statements)

References 26 publications

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“…Studies have shown that the biological effects of CaP coatings in vivo are related to the type of CaP material, Ca-phosphorus ratio, surface morphology, and additives [ [136] , [137] , [138] ]. Currently, researchers have proposed various strategies for functionalizing CaP coatings, including the addition of proteins, growth factors, and therapeutic ions to cope with complex internal environments [ [139] , [140] , [141] ]. Among them, Sr-containing CaP coatings are considered to be an effective strategy for inhibiting bone resorption at the implant interface and promoting bone integration.…”

Section: Srbmsmentioning

confidence: 99%

Advanced applications of strontium-containing biomaterials in bone tissue engineering

Sheng¹,

Li²,

Wang³

et al. 2023

Materials Today Bio

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Section: Srbmsmentioning

confidence: 99%

Advanced applications of strontium-containing biomaterials in bone tissue engineering

Sheng¹,

Li²,

Wang³

et al. 2023

Materials Today Bio

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“…The prepared CaPO 4 deposits were found to exhibit an XRD pattern resembling that of bone and, most importantly, contain trace elements. According to the authors: "This method requires only electrical stimulation and, therefore, it is a convenient method for collecting and supplying apatite as a biomaterial compared with conventional synthetic methods" [767].…”

Section: Electrical Stimulationmentioning

confidence: 99%

There Are over 60 Ways to Produce Biocompatible Calcium Orthophosphate (CaPO4) Deposits on Various Substrates

Dorozhkin

2023

J. Compos. Sci.

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A The present overview describes various production techniques for biocompatible calcium orthophosphate (abbreviated as CaPO4) deposits (coatings, films and layers) on the surfaces of various types of substrates to impart the biocompatible properties for artificial bone grafts. Since, after being implanted, the grafts always interact with the surrounding biological tissues at the interfaces, their surface properties are considered critical to clinical success. Due to the limited number of materials that can be tolerated in vivo, a new specialty of surface engineering has been developed to desirably modify any unacceptable material surface characteristics while maintaining the useful bulk performance. In 1975, the development of this approach led to the emergence of a special class of artificial bone grafts, in which various mechanically stable (and thus suitable for load-bearing applications) implantable biomaterials and artificial devices were coated with CaPO4. Since then, more than 7500 papers have been published on this subject and more than 500 new publications are added annually. In this review, a comprehensive analysis of the available literature has been performed with the main goal of finding as many deposition techniques as possible and more than 60 methods (double that if all known modifications are counted) for producing CaPO4 deposits on various substrates have been systematically described. Thus, besides the introduction, general knowledge and terminology, this review consists of two unequal parts. The first (bigger) part is a comprehensive summary of the known CaPO4 deposition techniques both currently used and discontinued/underdeveloped ones with brief descriptions of their major physical and chemical principles coupled with the key process parameters (when possible) to inform readers of their existence and remind them of the unused ones. The second (smaller) part includes fleeting essays on the most important properties and current biomedical applications of the CaPO4 deposits with an indication of possible future developments.

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A novel method for coating calcium phosphate with trace elements extracted from bone using electrical stimulation

Cited by 2 publications

References 26 publications

Advanced applications of strontium-containing biomaterials in bone tissue engineering

Advanced applications of strontium-containing biomaterials in bone tissue engineering

There Are over 60 Ways to Produce Biocompatible Calcium Orthophosphate (CaPO4) Deposits on Various Substrates

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