A novel method to fabricate porous tricalcium phosphate composite scaffolds for bone tissue engineering applications

Sankar, Sharanya; Ramajayam, Krishna Kumar; Thirugnanam, A.

doi:10.1080/10667857.2016.1151194

Cited by 3 publications

(2 citation statements)

References 23 publications

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“…The amount of micro-size pores was lower than that of NaCl-treated specimen. The formation of fine pores can be ascribed to the decomposition of calcium carbonate and gas release very similar to the mechanism of pore formation in the gas-foaming technique [48]. The effect of porogen on the size distribution is shown in Figure 4f.…”

Section: Microstructure Of Ha-biopolymer Scaffoldsmentioning

confidence: 59%

“…Based on the SEM images presented in Figure 4e, the use of NaHCO 3 particles (200-250 µm) resulted in the formation of micro-sized pores (100-300 µm), as well as very fine pores on the pore walls. The formation of very fine pores can be attributed to the decomposition of calcium carbonate and gas release, corresponding to the mechanism of pore formation in the gas-foaming technique [48].…”

Section: Discussionmentioning

confidence: 99%

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Extraction of Hydroxyapatite Nanostructures from Marine Wastes for the Fabrication of Biopolymer-Based Porous Scaffolds

et al. 2019

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Three-dimensional porous nanocomposites consisting of gelatin-carboxymethylcellulose (CMC) cross-linked by carboxylic acids biopolymers and monophasic hydroxyapatite (HA) nanostructures were fabricated by lyophilization, for soft-bone-tissue engineering. The bioactive ceramic nanostructures were prepared by a novel wet-chemical and low-temperature procedure from marine wastes containing calcium carbonates. The effect of surface-active molecules, including sodium dodecyl sulfate (SDS) and hexadecyltrimethylammonium bromide (CTAB), on the morphology of HA nanostructures is shown. It is demonstrated that highly bioactive and monophasic HA nanorods with an aspect ratio > 10 can be synthesized in the presence of SDS. In vitro studies on the bioactive biopolymer composite scaffolds with varying pore sizes, from 100 to 300 μm, determine the capacity of the developed procedure to convert marine wastes to profitable composites for tissue engineering.

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Section: Microstructure Of Ha-biopolymer Scaffoldsmentioning

confidence: 59%

Section: Discussionmentioning

confidence: 99%