A novel pyrene based highly selective reversible fluorescent-colorimetric sensor for the rapid detection of Cu²⁺ ions: application in bio-imaging

Abstract

A simple, low-cost pyrene derivative containing a benzilmonohydrazone moiety has been exploited for the selective detection of Cu2+ by colorimetric, absorption, emission and bio-imaging methods. The sensitivity of the fluorescence based assay is 7.8 nM for Cu2+, which is far below the limit mentioned in the World Health Organization.

Triazole-based novel bis Schiff base colorimetric and fluorescent turn-on dual chemosensor for Cu2+ and Pb2+: application to living cell imaging and molecular logic gates

“…Only a few Cu(II) based sensors that causes an increase in the uorescence intensity have been reported. 11 Hence, the design and synthesis of chemosensors with turn-on uorescence signal for Cu 2+ are in high interest for researchers in recent years. [12][13][14] Further, sensors with both colorimetric and turn on uorescence signal which can respond at extremely low concentration of analyte are in high demand in the analytical and scientic areas because such low concentration of analyte(s) can be presently detected by inexpensive instrumentations and synthetically complex molecular systems.…”

Optical Sensing of Copper and Its Removal by Different Environmental Technologies

“…Patra et. al developed three Schiff based fluorescent chemosensor for copper and one fluorescent off sensor for copper . The first sensor is pyrene based schiff base and active for absorption, emission enhancement along with successful bio‐imaging.…”

A brief review on novel pyrene based fluorometric and colorimetric chemosensors for the detection of Cu2+

“…Patra and co-workers have developed a chemosensor 31 containing a benzilmonohydrazone moiety for the detection of Cu 2+ . 94 The chemosensor 31 exhibited a significant colour chang e from yellow to colourless in the presence of 10 equiv . of Cu 2+ ions.…”