This chapter presents and details a complete IoT solution for secure, synchronous, low-power, wireless and unattended structural health monitoring (SHM), whose architecture can be parameterised to any type of structure to be monitored, thanks to its modular design based on an embedded real-time operating system at the node level and a microservices architecture at the application level. This solution is validated by means of its deployment, together with two commercial reference systems, in two experimental use cases in two different structures: on the one hand, a bridge located at the Engineering School of the University of Seville (Spain) and, on the other hand, the Homage Tower of the Utrera’s Castle (Spain). The results obtained place this work as a novel solution in the current state of the art.