A novel reactor for photochemical post-column derivatisation in HPLC

Construction and comparison of open tubular reactors for post-column reaction detection in liquid chromatography

“…Recently, this concept has been extended to, and the hydrodynamic equations explained and solved for, capillary supercritical fluid chromatography (6). The principles for improvements in radial mixing in coiled tubes have been exploited through the introduction of the KOT, also known as a three-dimensional coiled tube (1,7,8), but the equations for these reactors have not been solved to date.…”

An HPLC postcolumn reaction system for phosphorus-specific detection in the complete separation of inositol phosphate congeners in aqueous samples

“…If necessary, increasing the length of the 0.3-mm-diameter tubing in the bath may lead to a more complete reaction with a minimum of peak broadening. Use of crocheted tubing has been reported as a means to reduce the mixing problems (32,33) that produce peak Figure 5. Effect of reagent ratio on response (54 °C, tubing diameter 0.30 mm, flow 0.6 mL/min) for 1 mg of P04 P/L.…”

HPLC post column derivatization of aromatic amines usingN-methyl-9-chloroacridinium triflate

“…Since post-column derivatization systems require an additional reaction volume after the chromatographic separation, a properly designed reactor is important to N-Methyl-6,9-dichloro-2-methoxy-C1 C1 OCH 3 acridinium triflate achieve high sensitivity and selectivity without significant loss of chromatographic resolution due to band broadening phenomena [12][13][14][15][16][17][18][19][20][21]. Three basic types of post-column reactor systems have been used in flowing stream systems: opentubular reactors [12][13], packed-bed reactors [14], and phase segmented reactors [15].…”