A Novel Route for the Preparation of Gold Nanoparticles in Polycaprolactone Nanofibers

Abstract

A facile strategy for the fabrication of polycaprolactone (PCL) nanofibers containing gold nanoparticles (AuNPs) is proposed. The method is based on electrospinning nanosuspensions loaded with passivated Au nanoparticles. The optical property of gold nanoparticles synthesized was observed by UV-visible absorption spectra. Morphology and structure of the Au-PCL hybrid nanofibers were characterized by scanning electron microscopy, scanning transmission electron microscopy, and Fourier transformed infrared spectroscopy. The results of investigations by UV-visible and dynamic light scattering confirmed the presence of gold nanoparticles with diameters less than 10 nm. The STEM images show the presence of gold nanoparticles and gold agglomerates with diameter around 30 to 180 nm distributed over the surface of nanofibers, which is likely due to the increased incidence of agglomerations of AuNPs, due to drying process used.

In Vitro Macrophage Immunomodulation by Poly(ε-caprolactone) Based-Coated AZ31 Mg Alloy

“…The FTIR analysis of the tested materials’ surfaces showed similar spectra with all the signals corresponding only to the PCL polymer due to the technique’s inability to identify the loaded CM and ZnO nanoparticles. This phenomenon was also reported by Reyers-Lopez et al [ 88 ] on PCL electrospun nanofibers loaded with gold nanoparticles. The XPS results indicated the perfect coating of Mg alloy with the electrospun PCL mixtures by the presence only of O1s and C1s atoms.…”

Dose-Dependent Antimicrobial Activity of Silver Nanoparticles on Polycaprolactone Fibers against Gram-Positive and Gram-Negative Bacteria

“…Pharmaceutical industry uses polymer matrices as delivering systems for active principles. This methodology allows the fabrication of membranes for biomedical use as biological tissue regeneration for dressings, environmental remediation, and water treatment [2,7,8]. Although it has been reported previously in scientific literature, studies about synthesis, characterization, and antimicrobial activity of PCL nanofibers by electrospinning containing AgNPs against Gram-negative and Gram-positive bacterial strains, including multidrug resistant microorganisms, are necessary.…”

Nanofibrous cosmetic face mask for transdermal delivery of nano gold: synthesis, characterization, release and zebra fish employed toxicity studies

“…The PEO-Gel nanofibre system, resembles the infrared spectrum of PEO, but it also contain peaks corresponding to gelatin that appears at 1640 cm −1 (amide I of –C = O stretching couples with –C–N stretch) and 1540 cm −1 (amide II out of phase) [ 62 ]. A broader –OH stretching in the region of 3000–3500 cm −1 could suggest an H-bond formation in between the two polymers [ 65 , 70 ]. Peaks at 1342 cm −1 of –CH 2 symmetric wagging [ 46 ], 1466 cm −1 of –OH bending, 1240 cm −1 , 1278 cm −1 of –C–O– stretching [ 71 ], 1102 cm −1 of –C–O stretching[ 46 ] and 2850 cm −1 , 2920 cm −1 of symmetric and asymmetric stretching [ 72 ] suggests the main contribution is coming from PEO backbone.…”

“…7: 201266 stretch) and 1540 cm −1 (amide II out of phase) [62]. A broader -OH stretching in the region of 3000-3500 cm −1 could suggest an H-bond formation in between the two polymers [65,70]. Peaks at 1342 cm −1 of -CH 2 symmetric wagging [46], 1466 cm −1 of -OH bending, 1240 cm −1 , 1278 cm −1 of -C-O-stretching [71], 1102 cm −1 of -C-O stretching [46] and 2850 cm −1 , 2920 cm −1 of symmetric and asymmetric stretching [72] suggests the main contribution is coming from PEO backbone.…”