In this article, we propose a novel fractional generalization of the three-dimensional differential transform method, namely the ternary-fractional differential transform method, that extends its applicability to encompass initial value problems in the fractal 3D space. Several illustrative applications, including the Schrödinger, wave, Klein-Gordon, telegraph, and Burgers' models that are fully embedded in the fractal 3D space, are considered to demonstrate the superiority of the proposed method compared with other generalized methods in the literature. The obtained solution is expressed in a form of an α α α-fractional power series, with easily computed coefficients, that converges rapidly to its closed-form solution. Moreover, the projection of the solutions into the integer 3D space corresponds with the solutions of the classical copies for these models. This reveals that the suggested technique is effective and accurate for handling many other linear and nonlinear models in the fractal 3D space. Thus, research on this trend is worth tracking.