A novel signal amplification strategy based on the competitive reaction between 2D Cu-TCPP(Fe) and polyethyleneimine (PEI) in the application of an enzyme-free and ultrasensitive electrochemical immunosensor for sulfonamide detection

Xiao, Jiaxuan; Hu, Xialin; Wang, Kun; Zou, Yanmin; Gyimah, Eric; Yakubu, Salome; Zhang, Zhen

doi:10.1016/j.bios.2019.111883

Cited by 62 publications

(23 citation statements)

References 33 publications

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“…To date, many studies have been reported on Cu-TCPP-based electro-chemical sensors. Based on 2D Cu-TCPP (Fe) and polyethyleneimine (PEI), Xiao et al 31 proposed an electrochemical immunosensor for ultrasensitive detection of sulfonamides with a detection limit lower than 0.395 ng/mL. 2D Cu-TCPP (Fe) with peroxidase-like activity can catalyze the reduction of H 2 O 2 .…”

Section: ■ Introductionmentioning

confidence: 99%

Amplified Electrochemical Hydrogen Peroxide Sensing Based on Cu-Porphyrin Metal–Organic Framework Nanofilm and G-Quadruplex-Hemin DNAzyme

Chen

Bai

et al. 2020

ACS Appl. Mater. Interfaces

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A novel electrochemical hydrogen peroxide (H 2 O 2 ) sensor based on Cu-porphyrin(Cu-TCPP)/G-quadruplex-hemin nanocomposite was constructed by assembling two-dimensional Cu-TCPP metal−organic framework (MOF) nanofilm and G-quadruplex-hemin DNAzyme. The Cu-TCPP synthesized by the surfactantassisted method has a wrinkled two-dimensional nanofilm morphology, which gives it a large surface area and accessible active sites. Cu-TCPP exhibits peroxidase activity and good stability and can catalyze the reduction of H 2 O 2 . In addition, Cu-TCPP can be used as a nanocarrier for G-quadruplex-hemin DNAzyme with strong peroxidase activity to achieve "biological barcode" amplification and improve stability. The cooperative interaction of Cu-TCPP and G-quadruplex-hemin DNAzyme effectively amplifies the electrochemical response signal. Electrochemical studies have shown that the constructed sensor exhibits good electrochemical sensing performance with three linear ranges: 0.08 μM to 0.11 mM, 0.11−0.91 mM, and 0.91−8.1 mM, with sensitivities of 2315.86, 301.00, and 65.71 μA/(mM cm 2 ), respectively, and the detection limit was 0.03 μM. In addition, the sensor shows good selectivity. In summary, this study provides a simple and effective new strategy for electrochemical sensing based on twodimensional MOFs and artificial enzymes.

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Section: ■ Introductionmentioning

confidence: 99%

Amplified Electrochemical Hydrogen Peroxide Sensing Based on Cu-Porphyrin Metal–Organic Framework Nanofilm and G-Quadruplex-Hemin DNAzyme

Chen

Bai

et al. 2020

ACS Appl. Mater. Interfaces

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“…In addition, the materials themselves have high catalytic activity, electrical conductivity, and biocompatibility, exhibiting reduced overpotential that can accelerate signal transduction and amplify the signal, resulting in highly sensitive and specific biosensing detection. Furthermore, comprehensive analysis of past literature confirms that smart nanomaterials with the coupling of electrochemical methods significantly improve the analytical performance of the sensors [ 90 – 92 ]. Figure 3 shows the electrode modification strategy for the electrochemical detection of drugs.…”

Section: Biosensorsmentioning

confidence: 95%

Recent Advances and Perspectives on the Sources and Detection of Antibiotics in Aquatic Environments

Zeng

Chang

Liu

et al. 2022

Journal of Analytical Methods in Chemistry

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Water quality and safety are vital to the ecological environment, social development, and ecological susceptibility. The extensive use and continuous discharge of antibiotics have caused serious water pollution; antibiotics are widely found in freshwater, drinking water, and reservoirs; and this pollution has become a common phenomenon and challenge in global water ecosystems, as water polluted by antibiotics poses serious risks to human health and the ecological environment. Therefore, the antibiotic content in water should be identified, monitored, and eliminated. Nevertheless, there is no single method that can detect all different types of antibiotics, so various techniques are often combined to produce reliable results. This review summarizes the sources of antibiotic pollution in water, covering three main aspects: (1) wastewater discharges from domestic sewage, (2) medical wastewater, and (3) animal physiology and aquaculture. The existing analytical techniques, including extraction techniques, conventional detection methods, and biosensors, are reviewed. The electrochemical biosensors have become a research hotspot in recent years because of their rapid detection, high efficiency, and portability, and the use of nanoparticles contributes to these outstanding qualities. Additionally, the comprehensive quality evaluation of various detection methods, including the linear detection range, detection limit (LOD), and recovery rate, is discussed, and the future of this research field is also prospected.

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“…Drop‐casting is the most widely adopted method for modifying nanomaterials on the electrode surface (Gu et al., 2018; Kokulnathan et al., 2021). In some cases, drop‐casting of nanomaterials is supported by adhesive and dispersant such as Nafion and chitosan–acetic acid solution (Mutreja et al., 2016; J. Xiao et al., 2020). Although drop‐casting is a simple and convenient way to modify nanomaterials on electrodes, the physical immobilization methods still have poor firmness, which may affect the analytical performance of sensors.…”

Section: Flexible Sensing Strategies Based On Nanomaterialsmentioning

confidence: 99%

“…Although drop‐casting is a simple and convenient way to modify nanomaterials on electrodes, the physical immobilization methods still have poor firmness, which may affect the analytical performance of sensors. Electrodeposition (Mutreja et al., 2016; J. Xiao et al., 2020) is a rapid and efficient in situ process for depositing materials from the electrolyte onto electrode surfaces using suitable voltages without using reductants or oxidants, which provides a firm method for the modification of nanomaterials on the electrode. Several metal nanoparticles (D. Pang et al., 2019; Xiaojie Shi et al., 2020) and 2D materials (Duan, 2020) can be in situ fabricated on electrode within a specific voltage range by electrochemical techniques.…”

Section: Flexible Sensing Strategies Based On Nanomaterialsmentioning

confidence: 99%

“…J. Xiao et al. (2020) designed an “off” electrochemical immunosensor for ultrasensitive detection of sulfonamides, in which the synthesized 2D MOFs Cu‐TCPP(Fe) with a peroxidase‐like property was directly modified on the electrode surface as a signal tag for H 2 O 2 catalysis. After the capture of sulfonamides, the structure of Cu‐TCPP(Fe) could be destroyed by polyethyleneimine (PEI) from PEI‐GO@Ab 2 because of the strong affinity between PEI and Cu 2+ , leading to an activity change of Cu‐TCPP(Fe).…”

Section: Flexible Sensing Strategies Based On Nanomaterialsmentioning

confidence: 99%

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Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

Ren

et al. 2022

Food Frontiers

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Food safety as a public health issue has aroused worldwide concern. Food safety risks caused by the existence of food safety hazards in food may occur in all stages of the food supply chain. Thus, great emphasis is placed on sensitive, selective, and convenient analytical methods of various food safety hazards in food. At present, nanomaterials are at the forefront of various electrochemical sensing applications. Given their unique physical, chemical, and biological characteristics, nanomaterials are considered perfect candidates for the design of electrode surface to construct electrochemical sensors with excellent analytical performance. With the assistance of nanomaterials, electrochemical sensors are a potential alternative to conventional methods of food safety analysis. This review focuses on current research achievements of nanomaterial‐assisted electrochemical sensors for food safety analysis reported in recent 5 years. It highlights the different detection mechanisms for analytes, flexible sensing strategies based on nanomaterials, and portable miniaturized electrochemical devices. Finally, the challenges and limitations in the design of electrochemical sensors for food safety analysis are also discussed.

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A novel signal amplification strategy based on the competitive reaction between 2D Cu-TCPP(Fe) and polyethyleneimine (PEI) in the application of an enzyme-free and ultrasensitive electrochemical immunosensor for sulfonamide detection

Cited by 62 publications

References 33 publications

Amplified Electrochemical Hydrogen Peroxide Sensing Based on Cu-Porphyrin Metal–Organic Framework Nanofilm and G-Quadruplex-Hemin DNAzyme

Amplified Electrochemical Hydrogen Peroxide Sensing Based on Cu-Porphyrin Metal–Organic Framework Nanofilm and G-Quadruplex-Hemin DNAzyme

Recent Advances and Perspectives on the Sources and Detection of Antibiotics in Aquatic Environments

Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

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