A Novel Treatment For Temporomandibular Joint Internal Derangement: A Randomized controlled clinical study

Abstract

Background: Temporomandibular joint (TMJ) disorders are among the common causes of facial pain. Internal derangement is the most common intra-articular TMJ disorder.Objective: The aim of this study was to evaluate the efficacy of ozone application in arthrocentesis of temporomandibular joints with internal derangement. Patients and methods:Thirty patients were recruited in this study. They presented with limited function and pain related to the TMJ. They were randomly and equally divided in two groups; group 1 (study group), subjected to arthrocentesis using ozonized water and group 2 (control group), subjected to arthrocentesis with saline only. Visual analogue scale (VAS) pain scores and mouth opening were assessed preoperatively and at different intervals postoperatively.Results: Pain levels decreased in both groups however, a significant decrease in the study group was noted after one month and one year postoperatively. Maximal mouth opening improved for all patients in both groups and the significant increase was reported in the study group after one month, six months, and one year postoperatively. Conclusion:Ozone showed clinical efficacy during arthrocentesis of temporomandibular joint internal derangements.

The Efficacy of Ozonized Water Versus Ringer Lactate Arthrocentesis for the Treatment of Temporomandibular Joint Internal Derangement

“…However, group A reported better improvement in the mouth opening at T1 and T4. The ozonized water had a positive impact on such findings and this was in accordance with Elsholkamy, 14 2018 in his study, he stated that mouth opening improved significantly for all patients treated with ozonized water as the mean increased from 28 mm preoperatively to 41 mm postoperatively. The present study scored no significant association between sex and mouth opening, which is parallel with another study performed by Grossmann et al, 15 2019, who illustrated no association between the results of sex and mouth opening (P > 0.05).…”

Ozone for the treatment of temporomandibular joint disorders

“…Finally, Yamaner et al 17 reported no significant differences between treatments. On the other hand, concerning arthrocentesis with ozone, another three studies 20 21 22 reported an improvement in MMO in TMD treated with OT.…”

“…Then, 10 full-text articles were retrieved, 2 of which were excluded with reasons. Eight articles 16 17 18 19 20 21 22 23 reported the use of OT for the treatment of TMD and the data extracted from these studies are listed in Additional Table 1 . No gray literature matched the eligibility criteria.…”

“…The patients received 2 mL of ozonized water with 70 μg/mL. 20 21 22 Finally, Daif 23 injected 2 mL of ozone gas concentration at 10 μg/mL into the articular fossa of the TMJ. The injections were repeated twice per week for 3 weeks.…”

“…On the other hand, there was evidence of the OT used in temporomandibular joint arthrocentesis. Hammuda et al 20 and Elsholkamy 22 assessed pain with VAS in the TMJ with intraarticular disorder. The control group receives arthrocentesis with 2 mL of saline solution.…”