A novel two‐step kit for topical treatment of tinea pedis – an open study

Shemer, Avner; Davidovici, Batya B.; Nathansohn, Nir; Amichai, Boaz

doi:10.1111/j.1468-3083.2010.03576.x

Cited by 5 publications

(3 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…27 Additionally, another report revealed a novel two-step kit that includes a topical solution (0.5% climbazole and 14% glycolic acid) and a cream (0.5% climbazole and 2% urea) was found to be effective, well-tolerated, and safe in the treatment of moderate and severe tinea pedis. 20 Although topical corticosteroids should not be used for long periods in the treatment of tinea pedis because of the possibility of fungal proliferation, it may be preferred in patients with severe symptoms in the initial phase of treatment. 17 Foot baths containing green tea polyphenols were also found to be effective in improving symptoms of interdigital tinea pedis.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Acral manifestations of fungal infections

Kutlubay

Yardımcı

Kantarcıoğlu

et al. 2017

Clinics in Dermatology

View full text Add to dashboard Cite

Section: Accepted Manuscriptmentioning

confidence: 99%

Acral manifestations of fungal infections

Kutlubay

Yardımcı

Kantarcıoğlu

et al. 2017

Clinics in Dermatology

View full text Add to dashboard Cite

“…[35][36][37][38][39][40][41][42][43][44][45] In one study of the 169 employees at 21 swimming pools in the Netanya area, Israel, 78 (46%) of the employees had concurrent onychomycosis and tinea pedis and 50 (30%) had tinea pedis only; the diagnosis was based on KOH microscopy and fungal culture. 46 Past history of tinea pedis, concurrent tinea pedis amongst family members, hot humid climates, hyperhidrosis (especially plantar hyperhidrosis), prolonged exposure of the feet to water, communal bathing/sharing washing facilities, use of public swimming pools, insufficient foot care, poor personal hygiene, maceration or breaks in the pedal skin, diabetes mellitus, peripheral vascular disease, atopic dermatitis, psoriasis, obesity, immunodeficiency, depression, schizophrenia, and genetic predisposition or susceptibility are other predisposing factors. [47][48][49][50][51][52][53][54][55][56][57][58]…”

Section: Epidemiologymentioning

confidence: 99%

Tinea pedis: an updated review

Leung¹,

Barankin²,

Lam³

et al. 2023

DIC

View full text Add to dashboard Cite

Background Tinea pedis is one of the most common superficial fungal infections of the skin, with various clinical manifestations. This review aims to familiarize physicians with the clinical features, diagnosis and management of tinea pedis. Methods A search was conducted in April 2023 in PubMed Clinical Queries using the key terms ‘tinea pedis’ OR ‘athlete’s foot’. The search strategy included all clinical trials, observational studies and reviews published in English within the past 10 years. Results Tinea pedis is most often caused by Trichophyton rubrum and Trichophyton interdigitale . It is estimated that approximately 3% of the world population have tinea pedis. The prevalence is higher in adolescents and adults than in children. The peak age incidence is between 16 and 45 years of age. Tinea pedis is more common amongst males than females. Transmission amongst family members is the most common route, and transmission can also occur through indirect contact with contaminated belongings of the affected patient. Three main clinical forms of tinea pedis are recognized: interdigital, hyperkeratotic (moccasin-type) and vesiculobullous (inflammatory). The accuracy of clinical diagnosis of tinea pedis is low. A KOH wet-mount examination of skin scrapings of the active border of the lesion is recommended as a point-of-care testing. The diagnosis can be confirmed, if necessary, by fungal culture or culture-independent molecular tools of skin scrapings. Superficial or localized tinea pedis usually responds to topical antifungal therapy. Oral antifungal therapy should be reserved for severe disease, failed topical antifungal therapy, concomitant presence of onychomycosis or in immunocompromised patients. Conclusion Topical antifungal therapy (once to twice daily for 1–6 weeks) is the mainstay of treatment for superficial or localized tinea pedis. Examples of topical antifungal agents include allylamines (e.g. terbinafine), azoles (e.g. ketoconazole), benzylamine, ciclopirox, tolnaftate and amorolfine. Oral antifungal agents used for the treatment of tinea pedis include terbinafine, itraconazole and fluconazole. Combined therapy with topical and oral antifungals may increase the cure rate. The prognosis is good with appropriate antifungal treatment. Untreated, the lesions may persist and progress.

show abstract

“…Tinea pedis is a common fungal infection seen worldwide, with the most prevalent dermatophytes isolated in these cases being T. rubrum, T. mentagrophytes, and Epidermophyton floccosum [18,[34][35][36]. This infection has been growing over recent years, yet the underlying pathogenesis is not definitively known [41,42]. However, tinea pedis was shown to be more prevalent in the adult-aged population, especially in males [34,35].…”

Section: Clinical Perspectives Of Tineamentioning

confidence: 99%

Dermatophyte Infections Worldwide: Increase in Incidence and Associated Antifungal Resistance

Kruithoff,

Gamal,

McCormick

et al. 2023

Life

View full text Add to dashboard Cite

The increase in incidence of superficial fungal infections combined with the emergence of antifungal resistance represents both a global health challenge and a considerable economic burden. Recently, dermatophytes, the main culprit causing superficial fungal infections, have started to exhibit antifungal resistance. This can be observed in some of the most common species such as Trichophyton rubrum and Trichophyton mentagrophytes. Importantly, the new subspecies, known as Trichophyton indotineae, has been reported to show high resistance to terbinafine, a first-line treatment for dermatophyte infections. Compounding these issues is the realization that diagnosing the causative infectious agents requires using molecular analysis that goes beyond the conventional macroscopic and microscopic methods. These findings emphasize the importance of conducting antifungal susceptibility testing to select the appropriate antifungal necessary for successful treatment. Implementing these changes may improve clinical practices that combat resistant dermatophyte infections.

show abstract

A novel two‐step kit for topical treatment of tinea pedis – an open study

Abstract: This novel treatment was found to be effective, well tolerated and safe in the treatment of moderate and severe tinea pedis during the active and the preventive stages.

Cited by 5 publications

References 10 publications

Acral manifestations of fungal infections

Acral manifestations of fungal infections

Tinea pedis: an updated review

Dermatophyte Infections Worldwide: Increase in Incidence and Associated Antifungal Resistance

Contact Info

Product

Resources

About