A novel zipper device versus sutures for wound closure after surgery: a systematic review and meta‐analysis

Xie, Chengxin; Yu, Chengqiang; Wang, Wei; Wang, Chenglong; Yin, Dong

doi:10.1111/iwj.13460

Cited by 6 publications

(6 citation statements)

References 29 publications

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“…One device, the Zipline (Zipline Medical, Inc., Styrker Corporation, Kalamazoo, MI), approximates skin edges after surgery and offsets skin tension. 25 Like the FMTB, it can also be used as an alternative to superficial sutures and is positioned immediately after surgery. Clinical studies either did not establish differences or superiority in wound outcomes or concluded the device was contraindicated in high-tension wounds, but established improvements in scar outcomes.…”

Section: Discussionmentioning

confidence: 99%

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Postoperative Mechanomodulation Decreases T-Junction Dehiscence After Reduction Mammaplasty: Early Scar Analysis From a Randomized Controlled Trial

Panton,

Vingan,

Barillas

et al. 2023

Aesthetic Surgery Journal

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Background Mechanical and tensile forces play an important role in postoperative wound healing. Mitigating soft tissue and cutaneous tension is a key consideration in aesthetic and reconstructive procedures, as it is an important contributor to complicated wound healing and poor scar cosmesis after surgery. Objectives The study objective was to assess the efficacy of the force modulating tissue bridge (FMTB) (“Brijjit”, Brijjit Medical Inc, Atlanta, GA) in reducing mechanical tension on postoperative wounds in patients, using the vertical incision of a Wise-pattern reduction mammaplasty as a clinical model. Methods The authors conducted a prospective, single-center, randomized, within-subject clinical trial to evaluate wound healing and nascent scar formation after 8 weeks of postoperative wound support with FMTB. Patients received standard of care (SOC) subcuticular closure on the vertical incision of one breast and experimental closure using FMTB on the contralateral incision after Wise-pattern reduction mammaplasty. Dimensions of the nascent scar were analyzed using three-dimensional wound analysis and rates of T-junction dehiscence evaluated using in-person clinical assessment at 2-, 4-, 6-, and 8-week follow-up visits. Results Thirty-four patients (n = 68 breasts) completed 8 weeks of postoperative FMTB application. There was a reduced rate of early T-junction wound dehiscence in FMTB breasts (n = 1) compared to SOC breasts (n = 11) (p < 0.01; NNT = 3 breasts). Mean vertical incision wound area during the intervention period was decreased in the FMTB breast (1.5 cm2) compared to the SOC breast (2.1 cm2) (difference, 0.57; 95% CI: 0.30 to 0.85; p < 0.01) and was significantly lower at 2- (p < 0.01), 4- (p < 0.01) and 8-week (p < 0.01) follow-up. Only the closure method was significantly associated with variations in Week 8 wound area (p < 0.01) after linear regression modeling. No serious adverse events occurred. Conclusions Force modulating tissue bridges decrease nascent scar dimensions and reduce the occurrence of wound dehiscence. This represents the first level I evidence of using continuous mechanomodulation to reduce postoperative wound complications after skin closure.

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Section: Discussionmentioning

confidence: 99%

“… 26-28 A 2020 meta-analysis comparing the Zipline to suture closure found a decreased rate of skin/soft tissue infection and decreased incision closure time but did not find a significant difference in rates of dehiscence. 25 Additionally, the study did not involve patients undergoing breast surgery.…”

Section: Discussionmentioning

confidence: 99%

Postoperative Mechanomodulation Decreases T-Junction Dehiscence After Reduction Mammaplasty: Early Scar Analysis From a Randomized Controlled Trial

Panton,

Vingan,

Barillas

et al. 2023

Aesthetic Surgery Journal

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“…There are other adhesive tape-based wound closure devices14 15 that are claimed to overcome the problems associated with current products by eliminating need for anaesthesia and reducing closure time in surgical wounds 16 17. However, there is no evidence18 to support their use in traumatic wounds. One new wound closure device is microMend, which contains a small array of miniature staples (microstaples) attached to a polyurethane backing, coated with acrylic adhesive, about the size and shape of a butterfly closure.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of microMend wound closure device in repairing skin lacerations

et al. 2023

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BackgroundmicroMend, a novel microstaple skin closure device, may be able to close simple lacerations. This study aimed to evaluate the feasibility and acceptability of using microMend to close these wounds in the ED.MethodsThis was an open-label, single-arm clinical study conducted at two EDs within a large urban academic medical centre. Wounds closed with microMend underwent assessments performed at days 0, 7, 30 and 90. Photographs of treated wounds were rated by two plastic surgeons using a 100 mm visual analogue scale (VAS) and a wound evaluation scale (WES), which has a best possible score of 6. Participants rated pain during application and both participants and providers rated their satisfaction with the device.ResultsThirty-one participants were enrolled in the study: 48% were female and the mean age of participants was 45.6 (95% CI 39.1 to 52.1). The mean wound length was 2.35 cm (95% CI 1.77 to 2.92), with a range of 1–10 cm. Mean VAS and WES scores at day 90 as evaluated by two plastic surgeons were 84.1 mm (95% CI 80.2 to 87.9) and 4.91 (95% CI 4.54 to 5.29), respectively. The mean pain score with application of the devices was 7.28 mm (95% CI 2.88 to 11.68) on a scale of 0–100 mm using VAS. Local anaesthesia was used in 9 patients (29%, 95% CI 20.7 to 37.3) of participants (of whom 5 required deep sutures). Ninety per cent (90%) of participants rated their overall assessment of the device as excellent (74%) or good (16%) at day 90. There were no serious adverse events in any participants in the study.ConclusionmicroMend appears to be an acceptable alternative for closing skin lacerations in the ED, providing good cosmetic results, with high levels of satisfaction by patients and providers. Randomised trials are needed to compare microMend with other wound closure products.Trial registration numberNCT03830515.

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“…Therefore, the development of novel wound closure technologies has become one of the research hotspots in the field of tissue engineering. In the past decades, various wound closure techniques have been developed, including wound adhesives, [ 9 ] vacuum‐assisted wound closure, [ 10 ] surgical zipper wound closure device, [ 11 ] and so on. Among them, wound adhesives stand out due to their following advantages: (1) Suitable for different types and shapes of wounds.…”

Section: Introductionmentioning

confidence: 99%

Hydrogel adhesives for generalized wound treatment: Design and applications

Pan

Zhang

et al. 2022

Journal of Polymer Science

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Wound refers to the place where human body is injured and ruptured. So, wounds in a broad sense include not only skin wounds, but also damages of muscle, corneal, heart, and lung, etc. As "gold standard" of wound closure, suture and staple cause secondary damage to the tissue, and require professional skills and equipment, so noninvasive hydrogel adhesives have been developed as an alternative to close and treat different kinds of wounds. However, the existing reviews mainly discussed the research of hydrogel adhesives for skin wounds, and the focus is mostly on its types and adhesion mechanisms, but a review comprehensively discusses the design and application of hydrogel adhesives on generalized wounds for wound closure and wound healing and the unique needs of various wounds for hydrogel adhesives is still lacking. In this review, the types and adhesion mechanisms of hydrogel adhesives will be briefly described, then the research progress of hydrogel adhesives in wound treatment is reviewed in detail from two aspects: the comprehensive design principles and the unique requirements of different types of wounds. Overall, we expect that this review will provide guidance for the development of hydrogel adhesives as new avenues for generalized wound care and treatment.

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A novel zipper device versus sutures for wound closure after surgery: a systematic review and meta‐analysis

Cited by 6 publications

References 29 publications

Postoperative Mechanomodulation Decreases T-Junction Dehiscence After Reduction Mammaplasty: Early Scar Analysis From a Randomized Controlled Trial

Postoperative Mechanomodulation Decreases T-Junction Dehiscence After Reduction Mammaplasty: Early Scar Analysis From a Randomized Controlled Trial

Evaluation of microMend wound closure device in repairing skin lacerations

Hydrogel adhesives for generalized wound treatment: Design and applications

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