A ns-μs duration, millitesla, exponential decay pulsed magnetic fields generator for tumor treatment

Mi, Yan; Yao, Chenguo; Jiang, Chun Yang; Li, Chengxiang; Sun, Caixin; Tang, Liling; Liu, Huan

doi:10.1109/tdei.2011.5976103

Cited by 6 publications

(4 citation statements)

References 25 publications

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“…In [7], the solid-state DC/DC boost front-end and h-bridge output are used to achieve the purpose of rapid current rise. In order to realize the output current steep pulse, literatures [8] and [9] respectively put forward the method of using high-voltage dc power supply and increasing boost charging circuit to charge capacitor during pulse current commutation. In order to improve the quality stability of transmitting current waveform, a method for suppressing the ripple current of the flat-top section of the emission current by introducing a passive bypass circuit in [10], and reference [11] proposed a high precision mixed-signal (analog and digital) plan for output current stabilization.…”

Section: Introductionmentioning

confidence: 99%

A Wide-Frequency Constant-Amplitude Transmitting Circuit for Frequency Domain Electromagnetic Detection Transmitter

Wang

Yao

et al. 2019

Electronics

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In this paper, a novel AC magnetic transmitter current source circuit is proposed for application of frequency domain electromagnetic method (FEM) prospecting. The proposed current source circuit is capable of generating high frequency and high constant amplitude currents, which are key technical problems for FEM. It is suitable for very wide frequencies. The main circuit of the proposed current source consists of a rising-edge enhancing unit, a constant current control unit, and a high voltage clamping unit. Large constant clamping voltage is applied during the rising edge and the falling edge of the alternating square current to obtain a high frequency and high linearity current source. On the current flat stage, the constant current unit provides the energy to the load to ensure the constant amplitude of the output current. Detailed operations of the proposed magnetic current source are given. Simulation and experimental results demonstrate that the proposed circuit achieves short reversal time, the linearity of the rising/falling edge, constant amplitude and low power loss. These are the desired characteristics of the ac square current source probing transmitter for the magnetic FEM applications.

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Section: Introductionmentioning

confidence: 99%

A Wide-Frequency Constant-Amplitude Transmitting Circuit for Frequency Domain Electromagnetic Detection Transmitter

Wang

Yao

et al. 2019

Electronics

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“…Generally, traditional PMF systems use single-coil system or Helmholtz coil system to generate a magnetic field. Sachiko Yamaguchi [2] and Mi et al [11][12][13] conducted experiments on tumor treatment with PMF generator using single-coil system and Helmholtz coil system, respectively.…”

Section: Introductionmentioning

confidence: 99%

Development of a focusing pulsed magnetic field system for in Vivo experiments

Jiang

Yao

et al. 2013

IEEE Trans. Dielect. Electr. Insul.

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The design of a spherical coil system for pulsed magnetic field (PMF) exposure is presented for in vivo experiments with tumor-bearing animals. The system has greater focusing capability than conventional systems and has advantages in terms of effectiveness and safety. In the simulation part of the study, the magnetic field distribution of two spherical coil systems were studied using a finite element code, where the influences of coil radius and wire diameter were analyzed to optimize the final design. The simulation results indicate that the coil radius has significant effects on the magnetic field distribution, while the effect of wire diameter is negligible. Based on the designed parameters, a coil system was then developed and the magnetic field focusing ability of the system was measured and evaluated. The coil system has a better focusing performance with the central magnetic induction B m of 1.3×10 -4 T and S 80% of 2.8×10 -3 m 2 . The spherical coil system contributes to the system's focusing ability, which is expected to help in experiments for tumor treatment in the near future.Index Terms -Focusing magnetic field coil system, pulsed magnetic field exposure system, spherical coil system, tumor-bearing animals, finite-element simulation

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“…INTRODUCTION 1 Nowadays technology on magnetic field strength measurement have made great progress and been widely applied to industry, agriculture, science of national defense and biomedical engineering [1][2][3]. In recent decades, repetitive Transcranial Magnetic Stimulation (rTMS) played more and more critical roles in cranial nerve and brain research while pulse magnetic field (PMF) involved in rTMS is of microsecond level.…”

mentioning

confidence: 99%

“…Most PMF detecting and measuring technologies are focusing on strong pulsed magnetic field (sPMF) used in atom structure research and weak pulsed magnetic field (wPMF) at nanosecond level conducted in transformer substation, but when it comes to wPMF in medical instruments application * they cannot meet demands [3][4][5][6][7][8]. Comparing to magneto-optical effect method used for sPMF, electromagnetic induction method based on Faraday's Law is more feasible for wPMF measurement, which has advantages of wide measuring range and high sensitivity without any constraint in signal frequency.…”

mentioning

confidence: 99%

Study on technology of high-frequency pulsed magnetic field strength measurement

Chen

Liu

Yin

2012

2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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High-frequency transient weak magnetic field is always involved in researches about biomedical engineering field while common magnetic-field sensors cannot work properly at frequencies as high as MHz. To measure the value of MHz-level weak pulsed magnetic-field strength accurately, this paper designs a measurement and calibration method for pulsed magnetic-field. In this paper, a device made of Nonferromagnetic material was independently designed and applied to pulsed magnetic field measurement. It held an accurately relative position between the magnetic field generating coil and the detecting coil. By applying a sinusoidal pulse to the generator, collecting the induced electromotive force of the detector, the final magnetic field strength was worked out through algorithms written in Matlab according to Faraday's Law. Experiments were carried out for measurement and calibration. Experiments showed that, under good stability and consistency, accurate measurement of magnetic-field strength of a sinepulse magnetic-field can be achieved, with frequency at 0.5, 1, 1.5 MHz and strength level at micro-Tesla. Calibration results carried out a measuring relative error about 2.5%.

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A ns-μs duration, millitesla, exponential decay pulsed magnetic fields generator for tumor treatment

Cited by 6 publications

References 25 publications

A Wide-Frequency Constant-Amplitude Transmitting Circuit for Frequency Domain Electromagnetic Detection Transmitter

A Wide-Frequency Constant-Amplitude Transmitting Circuit for Frequency Domain Electromagnetic Detection Transmitter

Development of a focusing pulsed magnetic field system for in Vivo experiments

Study on technology of high-frequency pulsed magnetic field strength measurement

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