A Patency Capsule Remained Intact in the Colon over 210 Hours

Hihara, Yu; Joshita, Satoru; Takahashi, Toshiharu; Okaniwa, Shinji; Matsuo, Yoshiki; Nakamura, Yoshiyuki

doi:10.1155/2017/1201404

Cited by 3 publications

(5 citation statements)

References 4 publications

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“…Out‐of‐spec variations in PC dissolution time may be caused by too much or too little exposure to intestinal fluids, or by chewing the PC during ingestion. Some case reports have described a lack of PC dissolution because of low exposure to intestinal fluids 8 . In our case, the patient took Patency capsules at home after careful explanation and consent.…”

Section: Discussionmentioning

confidence: 77%

“…Some case reports have described a lack of PC dissolution because of low exposure to intestinal fluids. 8 In our case, the patient took Patency capsules at home after careful explanation and consent. Although medical personnel could not be present, the patient was a middle‐aged man without dementia with no problematic behavior regarding swallowing the Patency capsules, such as chewing the PCs.…”

Section: Discussionmentioning

confidence: 78%

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A case of incorrect evaluation of intestinal patency by early dissolution of a patency capsule

Omori,

Hara,

Murasugi

et al. 2023

DEN Open

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A 60‐year‐old man presented with a suspected small intestinal tumor on positron‐emission tomography‐computed tomography. Small bowel capsule endoscopy (SBCE) was planned for close examination of the small intestine. To avoid retention of the SBCE due to strictures, a patency capsule (PC) was first used to evaluate patency. However, PC discharge was not visually confirmed during the 24‐h period. No obvious PC was observed on plain abdominal radiography performed in the standing position. The patient underwent SBCE, assuming that the PC had been shed inconspicuously. SBCE revealed a neoplastic lesion with stenosis at a site thought to be the upper small intestine and remained stagnant at the same site for the duration of the battery. In addition, in the SBCE image, a PC shell was captured in the intestinal tract on the oral side of the stenosis. When the pre‐SBCE plain abdominal radiograph was enlarged to confirm the details, PC was observed in the lateral and decubitus views as a dissolved shell only. To the best of our knowledge, no previous report has described the complete dissolution of a PC leaving only its shell during a 30‐hour patency evaluation period. This case illustrates that, in the absence of visual confirmation of a PC discharge, PC may have remained in the body due to premature dissolution. Additional examinations or plain X‐ray imaging should be performed to confirm this, with no preconceived notions that the PC will not dissolve within 30 hours of administration.

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Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 78%

A case of incorrect evaluation of intestinal patency by early dissolution of a patency capsule

Omori,

Hara,

Murasugi

et al. 2023

DEN Open

View full text Add to dashboard Cite

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“…The maximum excretion time of intact capsule was 68 h after ingestion in our study. Surprisingly, Hihara et al [18] reported a case with excretion of an intact capsule > 210 h after PPC ingestion. They mean that the starting time for dissolution of timer plug is variable and that Following CE, the PPC was observed in the pelvis minor in an AXR or CT scan.…”

Section: Discussionmentioning

confidence: 99%

A Prospective Study Evaluating the Clinical Utility of the Tag-Less Patency Capsule with Extended Time for Confirming Functional Patency

et al. 2019

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Background: Patency confirmation is useful for avoiding the retention of capsule endoscopy (CE). We first evaluated the clinical utility of the tag-less PillCam^TM Patency Capsule (PPC) for up to 72 h after ingestion prospectively. Methods: Excretion of an intact capsule or intact body within 72 h, or positive PPC image in the colon or negative PPC image by abdominal X-ray at 30 h was defined as confirmed functional patency. In patients with unconfirmed functional patency, balloon-assisted enteroscopy was performed to evaluate the reason. Results: Functional patency was confirmed in 44 of 57 patients. Patency was confirmed in 38 patients (66.7%) at 30 h. In 6 of 19 patients (31.6%) in whom patency was not confirmed at 30 h, patency was confirmed within 72 h and no capsule retention (CR) occurred. The rate of pan-enteroscopy did not differ between patients whose patency was confirmed at 30 h and those whose patency was confirmed within 72 h. Excretion time of the PPC significantly correlated with that of the capsule (r = 0.650). Severe adhesions (>5 cm) interfered with PPC passage in 2 patients, despite the absence of critical stricture. The rate of no CR in patients with functional patency confirmed by prior PPC was 97.7%. Misjudgment of the location of the PPC is a risk for CR. Conclusions: Extending the time to confirm functional patency to 72 h may be acceptable and increase the possibility to perform CE safely in whom CE can perform intrinsically. University Hospital Medical Information Network registration No: 000002564.

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“…12 Tag-less PC-associated AEs, such as aspiration, residual parylene coating, SBO, prolonged disintegration, and perforation, have been reported only in case reports. [13][14][15][16][17][18][19] Therefore, we aimed to evaluate tag-less PC-related AEs in more detail for the appropriate use of the PC in the J-POP study and additional research among a total of 2578 patients.…”

Section: Introductionmentioning

confidence: 99%

“…Our previous multicenter prospective study (the Japanese Association for Capsule Endoscopy Survey on the Appropriate Use of the Patency Capsule [J‐POP] study) demonstrated that CE retention occurred in 0.51% of the enrolled 1096 patients 12 . Tag‐less PC‐associated AEs, such as aspiration, residual parylene coating, SBO, prolonged disintegration, and perforation, have been reported only in case reports 13–19 . Therefore, we aimed to evaluate tag‐less PC‐related AEs in more detail for the appropriate use of the PC in the J‐POP study and additional research among a total of 2578 patients.…”

Section: Introductionmentioning

confidence: 99%

Nationwide multicenter study on adverse events associated with a patency capsule: Additional survey of appropriate use of patency capsule study

Omori,

Ohmiya,

Watanabe

et al. 2023

J of Gastro and Hepatol

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Background and AimThe PillCam patency capsule (PC) without a radio frequency identification tag was released to preclude retention of the small bowel capsule endoscope (CE) in Japan in 2012. We conducted a multicenter study to determine tag‐less PC‐related adverse events (AEs).MethodsWe first conducted a retrospective survey using a standardized data collection sheet for the clinical characteristics of PC‐related AEs among 1096 patients collected in a prospective survey conducted between January 2013 and May 2014 (Cohort 1). Next, we retrospectively investigated additional AEs that occurred before and after Cohort 1 within the period June 2012 and December 2014 among 1482 patients (Cohort 2).ResultsOf the 2578 patients who underwent PC examinations from both cohorts, 74 AEs occurred among 61 patients (2.37%). The main AEs were residual parylene coating in 25 events (0.97%), PC‐induced small bowel obstruction, suspicious of impaction, in 23 events (0.89%), and CE retention even after patency confirmation in 10 events (0.39%). Residual parylene coating was significantly associated with Crohn's disease (P < 0.01). Small bowel obstruction was significantly associated with physicians with less than 1 year of experience handling the PC and previous history of postprandial abdominal pain (P < 0.01 and P < 0.03, respectively). CE retention was ascribed to erroneous judgment of PC localization in all cases.ConclusionsThis large‐scale multicenter study provides evidence supporting the safety and efficiency of a PC to preclude CE retention. Accurate PC localization in patients without excretion and confirmation of previous history of postprandial abdominal pain before PC examinations is warranted (UMIN000010513).

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A Patency Capsule Remained Intact in the Colon over 210 Hours

Cited by 3 publications

References 4 publications

A case of incorrect evaluation of intestinal patency by early dissolution of a patency capsule

A case of incorrect evaluation of intestinal patency by early dissolution of a patency capsule

A Prospective Study Evaluating the Clinical Utility of the Tag-Less Patency Capsule with Extended Time for Confirming Functional Patency

Nationwide multicenter study on adverse events associated with a patency capsule: Additional survey of appropriate use of patency capsule study

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