A pericardialis tamponád kórélettana, klinikuma és állatkísérletes vizsgálati lehetőségei

Abstract

Acute pericardial tamponade is one of the most emergent clinical scenarios in cardiac surgery. With numerous causes in the background, pericardial tamponade can lead to cardiogenic shock and death. In modern diagnostic era, the recognition of pericardial tamponade is simple, but its management and the long-term effects can still be challenging. Without the detailed understanding of the pathophysiological pathways diagnostic and therapeutic management plans of pericardial tamponade is very difficult. The aim of this review was to give a complex picture of pericardial tamponade, from its role in medical history to pathophysiology and its significance in surgical experimental models. Orv Hetil. 2018; 159(5): 163-167.

Fatal Cardiac Tamponade: The Lethal Progression of Acute-on-Chronic Pericardial Effusion

“…The clinical manifestations of tamponade, including reduced cardiac output, elevated venous pressures, and impaired filling of cardiac chambers, can lead to hemodynamic compromise and potentially fatal consequences. The swift transition from the stable pericardial effusion observed in previous imaging to tamponade physiology underscores the dynamic nature of this condition [ 7 ].…”

Peritoneal Carcinoma Unveiling a Hidden Threat: A Case of Malignant Pericardial Effusion

“…Slow-growing effusions, such as those caused by neoplasms or autoimmune illness, allow for the stretching of the pericardium, allowing for higher amounts to be accommodated, and effusions can reach fairly large amounts before leading to tamponade physiology. In brief, traumatic causes require smaller amounts of fluid to generate hemodynamic instability than medical etiologies such as malignancy, which can cause enormous volumes of fluid to build up in the pericardium before the patients become symptomatic [5].…”

Reduction of perioperative inflammatory reaction with exogenous methane

“…Among the major complications of cardiac surgical interventions, PT is considered as one of the most dramatic pathological conditions affecting both the macro-and microhaemodynamics of the human body. The lack of urgent treatment can lead to cardiogenic shock and is inevitably followed by multi-organ failure and death (28). PT is caused by fluid accumulation within the pericardial sac.…”