A PET and ESIPT-communicated ratiometric, turn-on chromo-fluorogenic sensor for rapid and sensitive detection of sarin gas mimic, diethylchlorophosphate

Ahamed, Sabbir; Mahato, Manas; Tohora, Najmin; Sultana, Tuhina; Sahoo, Rajkumar; Ghanta, Susanta; Das, Sudhir Kumar

doi:10.1016/j.talanta.2023.124448

Cited by 8 publications

(4 citation statements)

References 55 publications

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“…[15][16][17] While studies on the detection of nerve agents in the literature describe traditional instrumental recognition techniques such as gas chromatography (GC), 18 electrochemical sensors, 19 enzyme-based biosensors, 20 micro-cantilevers, 21 and highperformance liquid chromatography (HPLC), 22 several straightforward colorimetric and uorometric molecular probes have also been developed. [23][24][25][26][27] Fluorometric and colorimetric methods are the most interesting of the available techniques because of their high sensitivity, selectivity, and simplicity of real-time recognition. Diethylcyanophosphonate (DCNP) and diethylchlorophosphate (DCP) are common substitutes for the poisonous nerve agents sarin and tabun.…”

Section: Introductionmentioning

confidence: 99%

“…23 They also contributed to identifying poisonous nerve agents by employing turn-on chromo-fluorogenic sensors. 26 For quick detection of DCP, a phthalimide-based fluorescence turn-on chemosensor has been developed by Sultana and colleagues. 24 Tohora and co-workers developed a benzoxazole-based turn-on fluorosensor for fast detection of poisonous nerve agents that mimic DCP.…”

Section: Introductionmentioning

confidence: 99%

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Highly selective and sensitive chromogenic recognition of sarin gas mimicking diethylchlorophosphate

Mahato,

Sultana,

Maiti

et al. 2024

Anal. Methods

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Highly selective and sensitive chromogenic recognition of sarin gas mimicking diethylchlorophosphate

Mahato,

Sultana,

Maiti

et al. 2024

Anal. Methods

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“…Also, Ahamed et al . reported phthalimide‐based DCP sensors via photo‐induced electron transfer (PET) and excited state intramolecular proton transfer (ESIPT) ratiometric mechanisms [41]. Great effort and noteworthy approaches have been made to create fluorescent chemosensors to efficiently sense G‐series nerve agents [42–46].…”

Section: Introductionmentioning

confidence: 99%

A pyrene‐based chromo‐fluorogenic probe for specific detection of sarin gas mimic, diethylchlorophosphate

Chourasia,

Tohora,

Sultana

et al. 2024

Luminescence

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Nerve agents are becoming serious issues for the healthy and sustainable environment of modern civilization. Therefore, its detection and degradation are of paramount importance to the scientific community. In the present contribution, we have introduced a chromo‐fluorogenic pyrene‐based probe, (E)‐2‐methoxy‐3‐(pyren‐1‐ylimino)‐3,8a‐dihydro‐2H‐chromen‐4‐ol (PMCO) to detect sarin stimulant diethylchlorophosphate (DCP) in solution and gaseous phases. On inserting DCP in PMCO solution, a visual colorimetric change from yellow to clear colourless in daylight and highly intensified blue fluorescence was observed instantly under a 365 nm portable UV lamp light. PMCO has outstanding selectivity and high sensitivity with a limit of detection of 1.32 μM in dimethyl sulfoxide (DMSO) medium and 77.5 nM in 20% H2O‐DMSO. A handy strained paper strip‐based experiment was demonstrated to recognize DCP in a mixture of similar toxic analytes. A dip‐stick experiment was performed to identify DCP vapour, and may be used as an effective photonic tool. We also demonstrated real sample analysis utilizing different DCP‐spiked water samples and validating DCP detection even in various types of soils such as sand, field, and mud. Therefore, this present study provides an effective chemosensor for instant and on‐site detection of toxic nerve agents in dangerous circumstances.

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“…Fluorescent probes find widespread application in detection and labeling techniques, including the determination of biomolecular content, metal ions, pesticide residues as well as the tracing of molecules [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ]. Fluorescence probes based on excited-state intramolecular proton transfer (ESIPT) have been developed and designed [ 11 , 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Paying Comprehensive Attention to the Temperature-Dependent Dual-Channel Excited-State Intramolecular Proton Transfer Mechanism of Fluorescence Ratio Probe BZ-DAM

Gao,

Zhang,

et al. 2023

IJMS

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The mechanism of fluorescence detection of diethyl chlorophosphate (DCP) based on 2-substituted benzothiazole (BZ-DAM) was studied by a theoretical calculation method. It should not be ignored that both the BZ-DAM and the detection product BZ-CHO have two excited-state intramolecular proton transfer (ESIPT) channels. Density functional theory (DFT) and time-dependent DFT (TDDFT) theory were used to study the photophysical mechanism of two compounds in two channels in (acetonitrile) ACN solvent, and the temperature dependence of the two channels was given. Channel 1 is more likely to exist at low temperatures and channel 2 is more likely to exist at high temperatures. By theoretical analysis of the constructed potential energy curve, the hydrogen bond energy and electron-hole analysis, we confirmed that both molecules undergo ESIPT and intramolecular charge transfer (ICT) processes in channel 1 and ESIPT and twisted intramolecular charge transfer (TICT) coupling processes in channel 2. The formation of product BZ-CHO molecules led to a significant fluorescence blue-shift phenomenon and inhibited the ICT process, which confirmed that BZ-DAM could be used as a fluorescence probe for fluorescence detection. We sincerely hope that this work will not only help to clarify the excited-state dynamics behavior of the BZ-DAM probe but also provide a new idea for designing and optimizing a new chemical dosimeter.

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A PET and ESIPT-communicated ratiometric, turn-on chromo-fluorogenic sensor for rapid and sensitive detection of sarin gas mimic, diethylchlorophosphate

Cited by 8 publications

References 55 publications

Highly selective and sensitive chromogenic recognition of sarin gas mimicking diethylchlorophosphate

Highly selective and sensitive chromogenic recognition of sarin gas mimicking diethylchlorophosphate

A pyrene‐based chromo‐fluorogenic probe for specific detection of sarin gas mimic, diethylchlorophosphate

Paying Comprehensive Attention to the Temperature-Dependent Dual-Channel Excited-State Intramolecular Proton Transfer Mechanism of Fluorescence Ratio Probe BZ-DAM

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