A phase III, placebo controlled clinical trial of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis

Efficacy and Safety of Azithromycin 1.5% Eye Drops for Purulent Bacterial Conjunctivitis in Pediatric Patients

“…3,4,11 These levels even quite similar, were statistically different by bootstrap method (81.8% for tobramycin group versus 80% for azithromycin; P Ͻ 0.001). This could probably be explained by the washing effects induced by the higher number of instillations performed in the tobramycin group.…”

Comparative efficacy of marine Streptomyces formulation versus ciprofloxacin ophthalmic solution for treating Staphylococcus aureus-induced conjunctivitis in animal model

“…In other studies, the topical application of ophthalmic antibiotic solution and test solution has been administered four times a day or five times a day [12,13], while in our study with the minimum administration of drug twice a day we could find complete recovery from inflammation on the second day in RAM25C4 treated group and on third day in the ciprofloxacin treated group.…”

Ocular penetration of levofloxacin, ofloxacin and ciprofloxacin in eyes with functioning filtering blebs: investigator masked, randomised clinical trial

“…The MIC 90 values for fluoroquinolone sensitive bacteria of levofloxacin are approximately 50% lower than those of ofloxacin 10 11…”