A photoswitchable “turn-on” fluorescent chemosensor: Quinoline-naphthalene duo for nanomolar detection of aluminum and bisulfite ions and its multifarious applications

David, C. Immanuel; Jayaraj, Haritha; Prabakaran, G.; Velmurugan, K.; devi, D. Parimala; Rajendran, Kayalvizhi; Angamuthu, Abiram; Kannan, V. Rajesh; Nandhakumar, Raju

doi:10.1016/j.foodchem.2021.131130

Cited by 25 publications

(5 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The presence of Al in living systems creates different toxic effects. Another effect is the change in the natural structure and roles of proteins and enzymes in the glycolysis and TCA pathways, cells, tissues, central nervous system (CNS), and other organs [21]. Al as a strong Lewis acid prefers oxygen donor ligands, including phosphates, nucleotides, carboxylates and nucleic acids.…”

Section: Introduction 1heavy Metalsmentioning

confidence: 99%

Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method

2022

View full text Add to dashboard Cite

Heavy metals are essential for a wide range of biological processes, including the growth and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the body’s immunity, but their excessive intake is harmful. Specifically, they cause oxidative stress (OS) and generate free radicals and reactive oxygen species (ROS) in metabolism. In addition, the accumulation of heavy metals in humans can cause serious damage to different organs, especially respiratory, nervous and reproductive and digestive systems. Biologically, metal chelation therapy is often used to treat metal toxicity. This process occurs through the interaction between the ligand and a central metal atom, forming a complex ring-like structure. After metals are chelated with appropriate chelating agents, their damage in metabolism can be prevented and efficiently removed from the body. On the other hand, heavy metals, including Zn, Fe and Cu, are necessary for the suitable functioning of different proteins including enzymes in metabolism. However, when the same metals accumulate at levels higher than the optimum level, they can easily become toxic and have harmful effects toward biomolecules. In this case, it induces the formation of ROS and nitrogen species (RNS) resulting in peroxidation of biological molecules such as lipids in the plasma membrane. Antioxidants have an increasing interest in many fields due to their protective effects, especially in food and pharmaceutical products. Screening of antioxidant properties of compounds needs appropriate methods including metal chelating assay. In this study, a general approach to the bonding and chelating properties of metals is described. For this purpose, the basic principles and chemical principles of metal chelation methods, both in vivo and in vitro, are outlined and discussed. Hence, in the main sections of this review, the descriptions related to metal ions, metal chelating, antioxidants, importance of metal chelating in biological system and definitions of metal chelating assays as widely used methods to determine antioxidant ability of compounds are provided. In addition, some chemical properties, technical and critical details of the used chelation methods are given.

show abstract

Section: Introduction 1heavy Metalsmentioning

confidence: 99%

Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method

2022

View full text Add to dashboard Cite

show abstract

“…Figure A–C presents confocal, bright-field, and overlaid images of the three probes along with their metal complexes in E. coli bacteria. , The probes alone (10 μM) were examined without the addition of Ag + ions, which showed weak fluorescence as discussed regarding the fluorescence selectivity of metal ions. After the addition of Ag + (20 μM) to free probes, strong fluorescence is shown through the green channel.…”

Section: Real Sample Analysismentioning

confidence: 99%

Positional Isomeric Symmetric Dipodal Receptors Dangled with Rotatable Binding Scaffolds: Fluorescent Sensing of Silver Ions and Sequential Detection of l-Histidine and Their Multifarious Applications

Prabakaran

David

Suresh

et al. 2022

J. Agric. Food Chem.

Self Cite

View full text Add to dashboard Cite

Three simple dipodal artificial acyclic symmetric receptors, SDO, SDM, and SDP, driven by positional isomerism based on xylelene scaffolds were designed, synthesized, and characterized by 1 H NMR, 13 C NMR, and mass spectroscopy techniques. Probes SDO, SDM, and SDP demonstrated selective detection of Ag + metal ions and amino acid L-histidine in a DMSO−H 2 O solution (1:1 v/v, HEPES 50 mM, pH = 7.4). The detection of Ag + metal ions occurred in three ways: (i) inhibition of the photoinduced electron-transfer (PET) process, (ii) blueshifted fluorescence enhancement via the intramolecular chargetransfer (ICT) process, and (iii) restricted rotation of the dangling benzylic scaffold following coordination with a Ag + metal ion. Job's plot analysis and quantum yields confirm the binding of probes to Ag +

show abstract

“…A large body of literature on ion sensing using colorimetric and fluorescence methods employing varied sensing mechanisms is available. 21–36…”

Section: Introductionmentioning

confidence: 99%

“…A large body of literature on ion sensing using colorimetric and uorescence methods employing varied sensing mechanisms is available. [21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36] Although some literature is available on detecting inorganic arsenic anions (arsenite and arsenate), there are still research scopes and gaps in sensing studies. 15,22,[37][38][39][40][41][42][43] Most chemosensors for arsenic anions operate through uorogenic methods, requiring uorescence lamps and instruments for visualizing the detection process.…”

Section: Introductionmentioning

confidence: 99%