A phthalocyanine-fluorescein conjugate

Ün, İlker

doi:10.3906/kim-1207-61

Cited by 2 publications

(1 citation statement)

References 41 publications

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“…Besides, phthalocyanines are extremely stable, compared for example to chlorins absorbing at similar wavelengths but less photostable . A wide range of nanoparticles has been reported , when only a few examples of molecular theranostic for PDT are described . In most cases, imaging properties are fluorescence‐based, phthalocyanines being intrinsically good fluorescent probes .…”

Section: Introductionmentioning

confidence: 99%

Design of a Gd‐DOTA‐Phthalocyanine Conjugate Combining MRI Contrast Imaging and Photosensitization Properties as a Potential Molecular Theranostic

Tekdaş

Garifullin

Şentürk

et al. 2014

Photochem & Photobiology

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The design and synthesis of a phthalocyanine--Gd-DOTA conjugate is presented to open the way to novel molecular theranostics, combining the properties of MRI contrast imaging with photodynamic therapy. The rational design of the conjugate integrates isomeric purity of the phthalocyanine core substitution, suitable biocompatibility with the use of polyoxo water-solubilizing substituents, and a convergent synthetic strategy ended by the use of click chemistry to graft the Gd-DOTA moiety to the phthalocyanine. Photophysical and photochemical properties, contrast imaging experiments and preliminary in vitro investigations proved that such a combination is relevant and lead to a new type of potential theranostic agent.

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Section: Introductionmentioning

confidence: 99%

Design of a Gd‐DOTA‐Phthalocyanine Conjugate Combining MRI Contrast Imaging and Photosensitization Properties as a Potential Molecular Theranostic

Tekdaş

Garifullin

Şentürk

et al. 2014

Photochem & Photobiology

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Effect of Gibberellic Acid and Royal Jelly Injection on Some Productive, Reproductive and Physiological Traits in Matrouh Chickens Strain During Summer Season.

Ezzat¹,

Rizk²,

Mohamed³

et al. 2020

Journal of Productivity and Development

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A total of 168 laying hens and 21 cocks of Matrouh local strain at 24 weeks of age (At 43.93 % egg production)was used in a completely randomized design among seven treatment groups with three replicates per treatment group (8 hens and 1 cock per replicate).Birds are biweekly injected, up to 36 weeks of age (12 weeks). The 1 st treatment group of birds were injected with saline solution 0.9% only and served as control, The birds in 2 nd and 3 rd treatment groups, were injected subcutaneously with 100 and 200 μg Gibberellic acid (GA3)/kg body weight (BW), respectively. The 4 th and 5 th treatment groups were injected with50 and 100 μg Royal Jelly (RJ)/kg BW, respectively. The 6 th treatment group was injected subcutaneously with 50μg GA3 plus25μg RJ/kg BW. The 7 th treatment group was injected subcutaneously with 100 μg GA3 plus 50μg RJ/kg BW. The same 7 treatment groups were used also, on 21 cocks in individual batteries to take semen quality. The obtained results revealed that, Injection with 100 , 200 μg GA3 or50 , 100 μg RJ /kg BW of Matrouh chicks improved significantly (P<0.05 and P<0.01) body weight changes (BWC),fertility eggs %, hatchability/total eggs % and chicks hatch weight (g), sperm-cell concentration (X 10 9 /ml) and sperm motility (%), while significantly (P<0.05) decreased each of dead spermatozoa (%), sperm abnormalities (%), and acrosomal damage (%) as compared with the control group. Layers injected by 100 , 200 μgGA3/kg body weight showed significantly (P≤0. 05 and P≤0. 01) improved feed conversion ratio (FCR), egg production (EP)% and egg mass (EM) compared with those the groups 170 EZZAT et al. 50 , 100 μg RJ /kg BW and control groups through the whole of the experimental period. Injection with 50, 100 μg of RJ /kg BW caused to increase significantly (P≤0. 01) in IgG and IgM and primary and secondary antibody titer against sheep red blood cells (SRBC's) in hens as compared with100, 200 μg of GA3and the control group. Injection 100 , 200 μg of GA3 /kg BW caused to increase significantly (P≤0. 05 and P≤0. 01) in concentration of estrogen in hens and testosterone of cocks, FSH and LH in hens and cocks when compared with those in control group. In conclusion, injection with 100, 200 μg GA3 /kg BW improved productive, reproductive and physiological performance of males and females Matrouh. Furthermore, the RJ-treated groups had significantly improved immune responses in hens and the quality of semen parameters in cocks under summer season conditions in Egypt.

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A phthalocyanine-fluorescein conjugate

Cited by 2 publications

References 41 publications

Design of a Gd‐DOTA‐Phthalocyanine Conjugate Combining MRI Contrast Imaging and Photosensitization Properties as a Potential Molecular Theranostic

Design of a Gd‐DOTA‐Phthalocyanine Conjugate Combining MRI Contrast Imaging and Photosensitization Properties as a Potential Molecular Theranostic

Effect of Gibberellic Acid and Royal Jelly Injection on Some Productive, Reproductive and Physiological Traits in Matrouh Chickens Strain During Summer Season.

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