A pilot study on the clinical efficacy of Solanum xanthocarpum and Solanum trilobatum in bronchial asthma

Govindan, Sajeev Chakanalil; Viswanathan, S.; Vijayasekaran, V.; Alagappan, R

doi:10.1016/s0378-8741(98)00160-3

Cited by 112 publications

(68 citation statements)

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“…The test herbal product is an extract of 14 medicinal herbs: Adhatoda vasica (root [5]), Alpinia galanga (rhizome [6]), Carum copticum (seed [7]), Coriandrum sativum (seed [8]), Coscinium fenestratum (stem [9]), Cuminum cyminum (seed [10]), Evolvulus alsinoides (whole plant [11]), Glycyrrhiza glabra (root [12]), Hedyotis corymbosa (whole plant [13]), Piper longum (fruit [14]), Piper nigrum (fruit [15]), Premna herbacea (root [16]), Solanum xanthocarpum (whole plant [17]), and Zingiber officinale (rhizome [18]). …”

Section: Discussionmentioning

confidence: 99%

The effect of a herbal formulation on the incidence and severity of upper respiratory symptoms in healthy volunteers: an open-label, randomised controlled clinical trial

Goonaratna

Sooriyarachchi

2012

Ceylon Med. J.

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Introduction Many traditional preparations with varying combinations of herbs have been used for over 1500 years to treat upper respiratory ailments, and reduce their incidence and severity. Link Samahan ® is a formulation containing the extract of 14 such medicinal plants.Objectives To test the efficacy of Link Samahan ® in reducing the incidence and severity of upper respiratory symptoms in consenting healthy volunteers.Setting MAS Linea Aqua, a factory with over 3000 employees, having its own health care centre with a qualified matron and visiting medical officers. Methods 956 healthy volunteers took daily either one sachet of Link Samahan® in hot water (test group, n=465, mean age 29.5 ± 7.7 years, women 418) or only plain tea (control group n=491, mean age 29.7 ± 7.9, women 448), for 84 consecutive days, and recorded the incidence and severity of 15 upper respiratory symptoms daily in a purpose-designed form.Results At the end of 84 days, when compared to the control group, the average incidence of symptoms in the test group showed highly significant reductions at p<0.001 for 6 symptoms and at p<0.005 for 3 symptoms, and at p<0.05 for the remaining 6. Reduction of average incidence over time also was highly significant (p<0.001) for 2 symptoms and (p<0.005) for 7, and significant (p<0.05) for 4 symptoms, but only marginal for the balance 2. Severity was significantly reduced (p<0.05) for 7 symptoms, and reduced also for the other 8 according to descriptive analysis, though not significant at the 5% level. ConclusionsThe results indicate that Link Samahan ® taken as one sachet daily significantly reduces average incidence, incidence over time, and severity of 15 upper respiratory symptoms in healthy adults.

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Section: Discussionmentioning

confidence: 99%

The effect of a herbal formulation on the incidence and severity of upper respiratory symptoms in healthy volunteers: an open-label, randomised controlled clinical trial

Goonaratna

Sooriyarachchi

2012

Ceylon Med. J.

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“…Kantkari [23] Solanum surattense Bronchodilator, Decreases edema and secretions in the airway lumen Vasa [24][25] [26] …”

Section: Ayurvedic Herbs Botanical Name Mode Of Actionmentioning

confidence: 99%

Approach of Ayurveda and Yoga in the Management of Occupational Lung Diseases

Kumar¹

2017

WJPR

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Occupational exposure is a potential cause of almost all respiratory diseases. Several occupational agents and jobs have been identified as definite or probable causes of occupational lung diseases in various epidemiological studies. Occupational lung diseases include occupational asthma, silicosis, coal worker's pneumoconiosis, asbestosis, mesothelioma, byssinosis, hypersensitivity pneumonitis and lung cancer. Persons with simple disease may never experience symptoms, whereas complicated presentation results in severe respiratory debilitation and death. Occupational lung diseases usually misdiagnosed as COPD, pulmonary fibrosis, or other diseases leading to a delay in identification of the etiological factor. There is no treatment for any of the occupational lung diseases that can reverse the damage already done.Primary strategy in these ailments is prevention of occupational exposure. Long term approach of Ayurveda and Yoga could be beneficial in the management of occupational lung diseases by improving the lungs functions, reducing the susceptibility towards the inhaled particles & allergens, providing symptomatic relief and at the same time enhance quality of life and work performance of the patient.

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“…The root extract is used to cure urinary diseases, cough and hair fall. Leaf extract is useful in thetreatment of fever, cough, Asthma, Sore throat, Rheumatism and treated for gonorrhea, influenza and enteric fever 18 . Optimization of process parameters helps the production of high-qualitynanoparticles minimizing the variable interventions.…”

Section: Introductionmentioning

confidence: 99%

Comparative Modeling Approach Upon Synthesizing Silver Nanoparticles From Solanum virginianum

Baskaran¹,

Sridhar²,

Abinandan³

et al. 2017

Orient. J. Chem

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The major objective focusses on synthesizing silver nanoparticles (Ag-NPs) from Solanum virginianum under optimum conditions. In this study, mathematical tools such as central composite design (CCD) and artificial neural networking (ANN) used for identifying process optimizing parameters. The maximum wavelength recorded (λ=425 nm) using chemical mediated synthesis for the leaf extract. Based on the results, that plant extract concentration (15 g ml

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A pilot study on the clinical efficacy of Solanum xanthocarpum and Solanum trilobatum in bronchial asthma

Cited by 112 publications

References 1 publication

The effect of a herbal formulation on the incidence and severity of upper respiratory symptoms in healthy volunteers: an open-label, randomised controlled clinical trial

The effect of a herbal formulation on the incidence and severity of upper respiratory symptoms in healthy volunteers: an open-label, randomised controlled clinical trial

Approach of Ayurveda and Yoga in the Management of Occupational Lung Diseases

Comparative Modeling Approach Upon Synthesizing Silver Nanoparticles From Solanum virginianum

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