A pilot study on the effects of exercise on depression symptoms using levels of neurotransmitters and EEG as markers

Barclay, Timothy H.; Richards, Scott; Schoffstall, James; Magnuson, Chad; McPhee, Christine; Price, Josh; Aita, Stephen L.; Anderson, Audrey; Johnson, Dan; Price, Jerry

doi:10.4103/2395-2555.150273

Cited by 7 publications

(3 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this way, the analgesic effect of exercise has shown to be related to higher levels of endorphins [ 54 ]. Thus, the improvements on pain, mechanical pain sensitivity, and psychological distress achieved in our study could be related to the increase in neurotransmitters’ levels, especially, endorphins, release by the hypothalamus [ 50 , 51 , 54 ].…”

Section: Discussionmentioning

confidence: 94%

See 1 more Smart Citation

Immediate Effects of a Telerehabilitation Program Based on Aerobic Exercise in Women with Fibromyalgia

Hernando-Garijo

Ceballos‐Laita

Mingo-Gómez

et al. 2021

IJERPH

View full text Add to dashboard Cite

Background: We analyzed the immediate effects of a Telerehabilitation Program (TP) based on aerobic exercise in women with fibromyalgia (FM) syndrome during the lockdown declared in Spain due to the COVID-19 pandemic. Methods: A single-blind randomized controlled trial was designed. Thirty-four women with FM were randomized into two groups: TP group and Control group. The intervention lasted 15 weeks, with 2 sessions per week. The TP based on aerobic exercise was guided by video and the intensity of each session was monitored using the Borg scale. Pain intensity (Visual Analogue Scale), mechanical pain sensitivity (algometer), number of tender points, FM impact (Revised Fibromyalgia Impact Questionnaire), pain catastrophizing (Pain Catastrophizing Scale), physiological distress (Hospital Anxiety and Depression Scale), upper (Arm Curl Test) and lower-limb physical function (6-min Walk Test) were measured at baseline and after the intervention. Results: The TP group improved pain intensity (p = 0.022), mechanical pain sensitivity (p < 0.05), and psychological distress (p = 0.005), compared to the Control group. The Control group showed no statistically significant changes in any variable (p > 0.05). Conclusions: A TP based on aerobic exercise achieved improvements on pain intensity, mechanical pain sensitivity, and psychological distress compared to a Control group during the lockdown declared in Spain due to COVID-19 pandemic.

show abstract

Section: Discussionmentioning

confidence: 94%

“…Regular exercise has shown to modify the levels of neurotransmitters, neuromodulators, and the hypothalamic–pituitary function [ 50 , 51 ]. The changes in these elements are related to improvements on pain, stress, anxiety, and depression among others in patients with chronic pain [ 52 , 53 ].…”

Section: Discussionmentioning

confidence: 99%

Immediate Effects of a Telerehabilitation Program Based on Aerobic Exercise in Women with Fibromyalgia

Hernando-Garijo

Ceballos‐Laita

Mingo-Gómez

et al. 2021

IJERPH

View full text Add to dashboard Cite

show abstract

“…In this sense, AT is the most investigated type of exercise for the management of central sensitization due to the activation of the descending pain-inhibitory mechanism and/or endogenous opioid and cannabinoid systems, and one single session has shown to be effective for reducing pain in patients with chronic pain [ 52 ]. Thus, the improvements for pain and physical function achieved in the included studies could be related to the increase in neurotransmitters’ levels, especially, endorphins [ 53 , 54 , 55 , 56 , 57 ].…”

Section: Discussionmentioning

confidence: 99%

Strength Training vs. Aerobic Training for Managing Pain and Physical Function in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Ceballos-Laita,

Lahuerta-Martín,

Carrasco-Uribarren

et al. 2023

Healthcare

View full text Add to dashboard Cite

(1) Background: Strength training (ST) and aerobic training (AT) are the most recommended interventions in patients with knee OA. These recommendations are supported by high-quality evidence, but it is still unknow whether one type of exercise is superior to the other. Thus, the aim was to investigate whether one type of exercise (ST or AT) is superior to the other for improving pain and physical function in patients with knee osteoarthritis. (2) Methods: A systematic review and meta-analysis was carried out following the PRISMA statement. The search strategy was conducted in PubMed, PEDro, Scopus, Web of Science and Cochrane Library databases. Randomized controlled trials comparing ST and AT on pain intensity and physical function in patients with knee osteoarthritis were included. Methodological quality and risk of bias were assessed with a PEDro scale and risk-of-bias tool, respectively. The certainty of evidence was evaluated using GRADE guidelines. (3) Results: Four studies (6 publications) were included. The qualitative and quantitative synthesis showed that ST produces no more improvement in pain intensity (SMD after intervention: 0.02; 95%CI: −0.15, 0.19; I2: 0%; three studies; 426 patients) and physical function (SMD after intervention: 0.07; 95%CI: −0.10, 0.24; I2: 0%; three studies; 426 patients) compared to AT in patients with knee osteoarthritis. The certainty of evidence was rated as very low. (4) Conclusions: Both type of exercises showed clinical benefits in people with knee osteoarthritis, but no differences between ST and AT were found.

show abstract

Aerobic exercise training for adults with fibromyalgia

Bidonde

Busch

Schachter³

et al. 2017

Cochrane Database of Systematic Reviews

171

158

View full text Add to dashboard Cite

When compared with control, moderate-quality evidence indicates that aerobic exercise probably improves HRQL and all-cause withdrawal, and low-quality evidence suggests that aerobic exercise may slightly decrease pain intensity, may slightly improve physical function, and may lead to little difference in fatigue and stiffness. Three of the reported outcomes reached clinical significance (HRQL, physical function, and pain). Long-term effects of aerobic exercise may include little or no difference in pain, physical function, and all-cause withdrawal, and we are uncertain about long-term effects on remaining outcomes. We downgraded the evidence owing to the small number of included trials and participants across trials, and because of issues related to unclear and high risks of bias (performance, selection, and detection biases). Aerobic exercise appears to be well tolerated (similar withdrawal rates across groups), although evidence on adverse events is scarce, so we are uncertain about its safety.

show abstract

A pilot study on the effects of exercise on depression symptoms using levels of neurotransmitters and EEG as markers

Cited by 7 publications

References 32 publications

Immediate Effects of a Telerehabilitation Program Based on Aerobic Exercise in Women with Fibromyalgia

Immediate Effects of a Telerehabilitation Program Based on Aerobic Exercise in Women with Fibromyalgia

Strength Training vs. Aerobic Training for Managing Pain and Physical Function in Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Aerobic exercise training for adults with fibromyalgia

Contact Info

Product

Resources

About