A polyaniline functionalized NiFeP nanosheet array-based electrochemical immunosensor using Au/Cu<sub>2</sub>O nanocubes as a signal amplifier for the detection of SARS-CoV-2 nucleocapsid protein

Bai, Linquan; Shi, Yawei; Zhang, Xue; Cao, Xiaowei; Shi, Huanhuan; Lu, Wenbo

doi:10.1039/d3an00616f

Cited by 20 publications

(7 citation statements)

References 47 publications

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“…In the field of sensors, metal oxides have always been one of the best choices for biomimetic biochemical enzymes. With the help of metal oxides, Au/Cu 2 O nanotubes have peroxidase‐like activity [38] . Metal oxides are widely used in uric acid biosensors.…”

Section: Non‐enzymatic Uric Acid Electrochemical Biosensormentioning

confidence: 99%

Enzymatic and Non‐Enzymatic Uric Acid Electrochemical Biosensors: A Review

et al. 2023

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In recent years, the development of electrochemical biosensors for uric acid has made great achievements. Firstly, uric acid electrochemical biosensors were classified according to their reaction mechanism. Then, the reaction mechanism of the uric acid sensor and the application of nano‐modified materials were deeply analyzed from the perspective of non‐enzyme and enzymes. In this paper, the catalytic oxidation capacity, enzyme adsorption effect, conductivity, robustness, detection range, and detection limit of uric acid sensors were discussed and compared. Finally, the advantages of acid‐sensitive electrochemical biosensors were summarized, and the constructive recommendations were proposed for improving the deficiencies of acid biosensors. The potential for further development in this area was also discussed.

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Section: Non‐enzymatic Uric Acid Electrochemical Biosensormentioning

confidence: 99%

Enzymatic and Non‐Enzymatic Uric Acid Electrochemical Biosensors: A Review

et al. 2023

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“…[18][19][20][21] Gold nanoparticles, in specifically, have proven to be ideal for creating customized electrodes. [22][23][24] As a result, many organic and inorganic molecules are physically chemisorbed on gold nanoparticles without losing their catalytic properties. [25] Furthermore, gold nanoparticles enable the creation of one or more-dimensional electrode nanoarrays with signal-to-noise ratios several orders of magnitude higher than those produced with ordinary electrodes.…”

Section: Introductionmentioning

confidence: 99%

Electroless Deposition of Gold on a Glassy Carbon Electrode (GCE) Surface for Selective Detection of Hydrogen Peroxide

Imran Hossain,

Dutta,

Ahmed

et al. 2024

ChemistrySelect

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Electroless deposition technique was employed to coat the surface of a glassy carbon electrode (GCE) with nanoparticles of gold (AuNPs). Afterward, sulfur (S) components were immobilized onto this AuNPs/GC electrode via an in‐situ chemisorption approach that considerably enhanced the catalytic activity, conductivity, and persistent durability of the electrode. Scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and X‐ray photoelectron spectroscopy (XPS) were used to characterize the modified electrode surface. The experimental results indicated that the S−AuNPs/GC electrode exhibits outstanding catalytic activity for the selective detection of H2O2 (HP). SWV measurements showed that the electrochemical sensor has a wide linear range of 10 to 2500 μM and a heightened sensitivity of 50.08 μA mM−1 cm−2. The proposed HP sensor demonstrated adequate repeatability and durability, as well as interference‐free quantitative analysis capability.

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“…Traditionally, the glucose oxidation catalyst is an immobilized enzyme, but there is growing interest in developing nonenzymatic sensors . Enzymatic glucose sensors suffer from drawbacks due to denaturization of enzymes, which can occur due to variations in temperature, pH, and humidity. − Nonenzymatic sensors have been developed using a wide range of electrocatalysts. − …”

Section: Introductionmentioning

confidence: 99%

Nonenzymatic Glucose Sensor Using Bimetallic Catalysts

Ghosh,

Li,

Yates

2023

ACS Appl. Mater. Interfaces

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Bimetallic glucose oxidation electrocatalysts were synthesized by two electrochemical reduction reactions carried out in series onto a titanium electrode. Nickel was deposited in the first synthesis stage followed by either silver or copper in the second stage to form Ag@Ni and Cu@Ni bimetallic structures. The chemical composition, crystal structure, and morphology of the resulting metal coating of the titanium electrode were investigated by X-ray diffraction, energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, and electron microscopy. The electrocatalytic performance of the coated titanium electrodes toward glucose oxidation was probed using cyclic voltammetry and amperometry. It was found that the unique high surface area bimetallic structures have superior electrocatalytic activity compared to nickel alone. The resulting catalyst-coated titanium electrode served as a nonenzymatic glucose sensor with high sensitivity and low limit of detection for glucose. The Cu@Ni catalyst enables accurate measurement of glucose over the concentration range of 0.2−12 mM, which includes the full normal human blood glucose range, with the maximum level extending high enough to encompass warning levels for prediabetic and diabetic conditions. The sensors were also found to perform well in the presence of several chemical compounds found in human blood known to interfere with nonenzymatic sensors.

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A polyaniline functionalized NiFeP nanosheet array-based electrochemical immunosensor using Au/Cu₂O nanocubes as a signal amplifier for the detection of SARS-CoV-2 nucleocapsid protein

Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which emerged as a novel pathogen in 2019. The virus is responsible for...

Cited by 20 publications

References 47 publications

Enzymatic and Non‐Enzymatic Uric Acid Electrochemical Biosensors: A Review

Enzymatic and Non‐Enzymatic Uric Acid Electrochemical Biosensors: A Review

Electroless Deposition of Gold on a Glassy Carbon Electrode (GCE) Surface for Selective Detection of Hydrogen Peroxide

Nonenzymatic Glucose Sensor Using Bimetallic Catalysts

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A polyaniline functionalized NiFeP nanosheet array-based electrochemical immunosensor using Au/Cu2O nanocubes as a signal amplifier for the detection of SARS-CoV-2 nucleocapsid protein

Abstract: Coronavirus disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which emerged as a novel pathogen in 2019. The virus is responsible for...

Cited by 20 publications

References 47 publications

Enzymatic and Non‐Enzymatic Uric Acid Electrochemical Biosensors: A Review

Enzymatic and Non‐Enzymatic Uric Acid Electrochemical Biosensors: A Review

Electroless Deposition of Gold on a Glassy Carbon Electrode (GCE) Surface for Selective Detection of Hydrogen Peroxide

Nonenzymatic Glucose Sensor Using Bimetallic Catalysts

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Product

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A polyaniline functionalized NiFeP nanosheet array-based electrochemical immunosensor using Au/Cu₂O nanocubes as a signal amplifier for the detection of SARS-CoV-2 nucleocapsid protein