A Polydiacetylene‐based Colorimetric Adenosine Triphosphate Sensor: A Molecular Protecting Approach

Shin, Hyunjeong; Lee, Jong Pil; Kim, Jong Man

doi:10.1002/bkcs.12148

Bulletin Korean Chem Soc

2020

DOI: 10.1002/bkcs.12148

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A Polydiacetylene‐based Colorimetric Adenosine Triphosphate Sensor: A Molecular Protecting Approach

Hyunjeong Shin

Jong Pil Lee

Jong Man Kim

Abstract: A colorimetric polydiacetylene (PDA) sensor for the detection of ATP was developed based on a molecular protection strategy.

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2022

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Detection of ATP in Cancer Cells with A Label-Free Fluorescent Aptasensor

Liu

Liang²,

et al. 2022

Nanomedicine (Lond.)

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Aim: To develop a new detection technique for ATP in cancer cells using fluorescent biosensing. Materials & methods: This research presents a new label-free fluorescent aptasensor for ATP measurement that incorporates a DNA aptamer, SYBR Gold and single-walled carbon nanohorns. Results: The aptasensor showed selectivity toward ATP and a low limit of detection (37.6 nM). The linear detection range was 100–50,000 nM, and the fluorescence intensity and ATP concentration logarithm showed an excellent linear correlation (R2 = 0.9924). Conclusion: The developed aptasensor may be used to detect cellular ATP in cancer cells and could be employed for biological sample analysis. The benefits of the aptasensor, such as its simplicity, speed, cost–effectiveness, specificity and sensitivity, give it promising implications as a potentially adaptable sensing platform.

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Detection of ATP in Cancer Cells with A Label-Free Fluorescent Aptasensor

Liu

Liang²,

et al. 2022

Nanomedicine (Lond.)

View full text Add to dashboard Cite

show abstract

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A Polydiacetylene‐based Colorimetric Adenosine Triphosphate Sensor: A Molecular Protecting Approach

Abstract: A colorimetric polydiacetylene (PDA) sensor for the detection of ATP was developed based on a molecular protection strategy.

Cited by 1 publication

References 36 publications

Detection of ATP in Cancer Cells with A Label-Free Fluorescent Aptasensor

Detection of ATP in Cancer Cells with A Label-Free Fluorescent Aptasensor

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