2016
DOI: 10.1111/odi.12509
|View full text |Cite
|
Sign up to set email alerts
|

A practical guide to the oral microbiome and its relation to health and disease

Abstract: The oral microbiome is incredibly complex with the average adult harboring about 50 to 100 billion bacteria in the oral cavity, which represent about 200 predominant bacterial species. Collectively, there are approximately 700 predominant taxa of which less than 1/3 still have not yet been grown in vitro. Compared to other body sites, the oral microbiome is unique and readily accessible. There is extensive literature available describing the oral microbiome and discussing the roles that bacteria may play in or… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

6
195
0
4

Year Published

2016
2016
2023
2023

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 273 publications
(215 citation statements)
references
References 111 publications
6
195
0
4
Order By: Relevance
“…DNA sequences were taxonomically assigned by use of the customized BLAST program named ProbeSeq for HOMI NGS . In Probeseq DNA sequences are blasted against 692 unique reference sequences (14–40 bases long), which were developed based on taxonomic information retrieved from the HOMD database .…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…DNA sequences were taxonomically assigned by use of the customized BLAST program named ProbeSeq for HOMI NGS . In Probeseq DNA sequences are blasted against 692 unique reference sequences (14–40 bases long), which were developed based on taxonomic information retrieved from the HOMD database .…”
Section: Methodsmentioning
confidence: 99%
“…Although saliva is sterile when entering the oral cavity, a saliva sample harbors a diverse and individualized microbiota . Thus, the salivary microbiota is thought to be composed by bacteria shed from oral surfaces, especially the tongue and throat, which are constantly lubricated by saliva . However, differences in the salivary microbiota have been reported in periodontitis patients compared to orally healthy controls .…”
mentioning
confidence: 99%
“…), with contributions from Bacteroidetes, Actinobacteria and Fusobacteria totaling upwards of 95% of all identified oral microbiota (Figure 2)[171177]. Further diversity exists between the varied micro-ecologies of the mouth[174,178], such as the tooth surface, gingiva, hard and soft palate, and even regionally on the tongue (Figure 2)[173,176,179]. Local variation in site-specific “core” microbial members speaks to the heterogeneity of influences bacterial communities experience, including host factors such as age, diet, geography and oral health[180182].…”
Section: The Oral Microbiome and Bacterial Nitrate Reductionmentioning
confidence: 99%
“…The oral microbiome, including that of plaque biofilm associated with caries, however, is complex as determined from cultural [25, 26] and molecular [27] methods and comprises many different species [28]. An extended ecological hypothesis of plaque composition in relation to caries [29] suggested microbial dysbiosis in response to a low biofilm pH.…”
Section: Bacteria and Dental Cariesmentioning
confidence: 99%