A practical regimen for amiodarone use in preventing postoperative atrial fibrillation

Zebis, Lars R.; Christensen, Thomas; Thomsen, Henrik F.; Folkersen, Lars; Sørensen, Henrik Toft; Hjortdal, Vibeke E.

doi:10.1097/00003643-200706003-00007

Cited by 8 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Interestingly, our data matches in general the ndings found in another CE-P valves cohort study (stroke 1%, AMI 1%, atrioventricular-block 4% (21)). The incidence of POAF (36.4%) is however higher than some reports (11%) (27), which might be due to the de nition of POAF in regards to duration and the overall awareness in the ward, since it is comparable to other ndings (32%-39.5%) (20,29).…”

Section: Discussioncontrasting

confidence: 42%

Long-Term Survival After Carpentier-Edwards Perimount Aortic Valve Replacement in Denmark: A Multi-Centre Observational Study

Krasniqi

Kronby

Riber

2020

Preprint

View full text Add to dashboard Cite

Background: This study describes the long-term survival, risk of reoperation and clinical outcomes for patients undergoing solitary surgical aortic valve replacement (SAVR) with a Carpentier-Edwards Perimount (CE-P) bioprosthetic in Denmark. The renewed interest in SAVR is based on the questioning regarding the long-term survival since new aortic replacement technique such as transcatheter aortic-valve replacement (TAVR) probably have shorter durability, why assessment of long-term survival could be a key issue for patients.Methods: From November 1999 to November 2015 a cohort of a total of 1604 patients aged 20-91 undergoing solitary SAVR with CE-P in Western Denmark was obtained November 2018 from the Western Danish Heart Registry (WDHR). The primary endpoint was long-term survival from all-cause mortality. Secondary endpoints were survival free from major adverse cardiovascular and cerebral events (MACCE), risk of reoperation, cause of late death, patient-prothesis mismatch, risk of AMI, stroke, pacemaker or ICD implantation and postoperative atrial fibrillation (POAF). Time-to event analysis was performed with Kaplan-Meier curve, cumulative incidence function was performed with Nelson-Aalen cumulative hazard estimates. Cox regression was applied to detect risk factors for death and reoperation.Results: In-hospital mortality was 2.7% and 30-day mortality at 3.4%. The 5-, 10- and 15-year survival from all-cause mortality was 77%, 52% and 24%, respectively. Survival without MACCE was 80% after 10 years. Significant risk factors of mortality were small valves, smoking and EuroSCORE II ≥4%. The risk of reoperation was <5% after 7.5 years and significant risk factors were valve prosthesis-patient mismatch and EuroSCORE II ≥4%.Conclusions: Patients operated with for aortic valve replacement with a Carpentier-Edwards Perimount valve shows a very satisfying long-term survival. Future research should aim to investigate biological valves long-term durability for comparison of different SAVR to different TAVR in long perspective.

show abstract

Section: Discussioncontrasting

confidence: 42%

Long-Term Survival After Carpentier-Edwards Perimount Aortic Valve Replacement in Denmark: A Multi-Centre Observational Study

Krasniqi

Kronby

Riber

2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Twenty‐three studies (Refs. – contributing comparisons for the studies as Ref. provided comparisons for two doses of amiodarone) (total N = 3,950) met the inclusion⁄exclusion criteria (Fig.…”

Section: Resultsmentioning

confidence: 99%

Timing and Route of Amiodarone for Prevention of Postoperative Atrial Fibrillation after Cardiac Surgery: A Network Regression Meta‐analysis

Chatterjee

Sardar

Mukherjee

et al. 2013

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

“…The Western Denmark Heart Register does not distinguish between atrial flutter and atrial fibrillation and the occurrence is only registered during hospital admission. However, a study by Zebis et al [26] showed no occurrences of atrial flutter after CABG in a similar population and only a risk of 1% in developing atrial fibrillation after hospital discharge.…”

Section: Outcome Variablesmentioning

confidence: 93%

Does Creatine Phosphokinase MB Predict Long-Term Cardiac Death or Atrial Fibrillation?

Jeppesen¹,

Riber²,

Riber³

2019

OJTS

View full text Add to dashboard Cite

Objectives: Exploring the long-term consequences of elevated postoperative creatine phosphokinase MB as a surrogate measure of cardiac tissue damage subsequent to coronary artery bypass graft surgery (CABG). Methods: Prospective cohort study including 414 patients subjected to solitary CABG at Odense University Hospital from September 30, 2007, and backwards in time. According to individual postoperative peak creatine phosphokinase MB, patients were assigned to five subgroups. Kaplan Meier survival analysis and Cox proportional-hazard regression evaluated the predictive value of creatine phosphokinase MB on late death from cardiac cause and diagnosis of paroxysmal or persistent atrial fibrillation within 10-years after CABG. Results: There was a general numeric decrease in time to cardiac death with increasing postoperative creatine phosphokinase MB (Log-Rank 0.285). Creatine phosphokinase MB < 25 was significantly associated with both shortened extracorporeal circulation time (HR 0.42; 95% CI 0.30-0.57; p < 0.001) and aortic cross-clamp time (HR 0.54; 95% CI 0.40-0.73; p < 0.001) compared to creatine phosphokinase MB ≥ 100. No association between creatine phosphokinase MB and atrial fibrillation was identified. Postoperative atrial fibrillation occurred in 84 patients, whereof 21 later developed paroxysmal or persistent atrial fibrillation. There was a statistically significant 2.4-fold (HR 2.38; 95% CI 1.37-4.14; p = 0.002) increase in paroxysmal or persistent atrial fibrillation in patients with postoperative atrial fibrillation compared to patients in postoperative sinus rhythm. Conclusions: Postoperative creatine phosphokinase MB was not found predictive of late cardiac death or diagnosis of paroxysmal or persistent atrial fibrillation within 10 years after CABG. However, patients with postoperative atrial fibrillation had increased risk of later developing paroxysmal or persistent atrial fibrillation compared to patients in postoperative sinus rhythm.

show abstract

A practical regimen for amiodarone use in preventing postoperative atrial fibrillation

Cited by 8 publications

References 0 publications

Long-Term Survival After Carpentier-Edwards Perimount Aortic Valve Replacement in Denmark: A Multi-Centre Observational Study

Long-Term Survival After Carpentier-Edwards Perimount Aortic Valve Replacement in Denmark: A Multi-Centre Observational Study

Timing and Route of Amiodarone for Prevention of Postoperative Atrial Fibrillation after Cardiac Surgery: A Network Regression Meta‐analysis

Does Creatine Phosphokinase MB Predict Long-Term Cardiac Death or Atrial Fibrillation?

Contact Info

Product

Resources

About