A practical synthesis of aryl tetrafluoroethyl ethers via the improved reaction of phenols with 1,2-dibromotetrafluoroethane

AB-type monomers for the preparation of perfluorocycloalkene (PFCA) aryl ether polymers

“…The synthesis of TFVE compounds (Scheme 4) involves fluoroalkyl incorporation in the first step, with reported yields for this first step ranging from 22 to 98%: 22%, 85.4%, 77.9%, 98% [8]; 41%, 42% [29]; 95% [30]; 50% [10]; 72% [9]; 70% [14]; 40.9% [31]. The overall yield of TFVE monomers derived from bisphenols are reported to range from 27 to 55%: 54.5% [8]; 32.8%, 42.8% [29]; 60%, 81% [13]; 27% [10]; 23% [31].…”

Copper(0)-mediated fluoroalkylation of iodobenzene with 2-bromo-1,1,2,2-tetrafluoroethyl compounds: Investigation on the influence of R substituent on the reactivity of RCF2Cu species

“…2-Bromo-1,1,2,2-tetrafluoroethyl compounds were prepared by using previously known methods (Scheme 3) [12][13][14]. Deoxyfluorination of 2-bromo-2,2-difluoroacetophenones with diethylaminosulfur trifluoride (DAST) readily gave (2-bromo-1,1,2,2-tetrafluoroethyl)arenes 8a [12] and 8b.…”

1,2-Dibromotetrafluoroethane (Freon 114B2) as a building block for fluorine compounds

“…Using anhydrous potassium, or preferably, cesium carbonate as a base in dry DMSO the substitutions were completed in short time to afford high yields of the desired 2-bromotetrafluoroethyl ethers 3a-d with only trace amounts of the bromine reduction products 4a-d. Reduction of compounds 3a-d with zinc dust in acetic acid gave aryl tetrafluoroethyl ethers 4a-d [8].…”