A prognostic nomogram for colorectal cancer liver metastases after percutaneous thermal ablation

Wang, Yang; Zheng, Jiasheng; Chen, Hui; Hu, Chen; Sun, Bin; Wang, Haiyan; Shi, Qinsheng; Jiang, Long; Zhang, Honghai; Li, Wei

doi:10.1080/02656736.2017.1368095

Cited by 18 publications

(17 citation statements)

References 42 publications

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“…In addition, several prognostic factors of poor OS were identified: a tumor diameter > 3 cm, tumor location in the right colon, multiple tumors, extrahepatic metastases pre-RFA, and intrahepatic recurrence. These concur with previously reported prognostic factors ( 6 , 13 , 41 – 43 ), except for intrahepatic recurrence; this may be the reason that these investigators did not conduct further analysis into the relationship between intrahepatic recurrence and OS. However, intrahepatic recurrence may indicate the presence of more tumor cells in the blood, resulting in poor OS.…”

Section: Discussionsupporting

confidence: 91%

Ten-Year Outcomes of Percutaneous Radiofrequency Ablation for Colorectal Cancer Liver Metastases in Perivascular vs. Non-Perivascular Locations: A Propensity-Score Matched Study

et al. 2020

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Purpose: To compare long-term outcomes of percutaneous radiofrequency ablation for colorectal liver metastases in perivascular versus non-perivascular locations. Methods: This retrospective study included 388 consecutive patients with colorectal liver metastases (246 men, 142 women; age range 27-86 years) who underwent percutaneous radiofrequency ablation between January 2006 and December 2018. Propensity-score matching was performed for groups with perivascular and nonperivascular colorectal liver metastases. Rates of accumulative local tumor progression, overall survival, intra/extrahepatic recurrence, and complications were compared between the two groups. Results: We successfully matched 104 patients each in the perivascular and nonperivascular groups (mean age: 60.

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Section: Discussionsupporting

confidence: 91%

Ten-Year Outcomes of Percutaneous Radiofrequency Ablation for Colorectal Cancer Liver Metastases in Perivascular vs. Non-Perivascular Locations: A Propensity-Score Matched Study

et al. 2020

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“…This obviously helps to improve the clinical outcomes and safety of the treatment methods, which in turn leads to the expanded application of percutaneous ablation in the treatment of HCC. 18,[27][28][29] It is challenging, but also necessary, to keep abreast of these developments. The correct use of assistive technologies, equipment and image guidance methods under different ablative modalities will be essential for the optimal treatment results.…”

Section: Introductionmentioning

confidence: 99%

Challenges Facing Percutaneous Ablation in the Treatment of Hepatocellular Carcinoma: Extension of Ablation Criteria

Zhou

Yang

Zhou

et al. 2021

JHC

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As an emerging minimally invasive treatment method, percutaneous ablation is more and more widely used in the treatment of liver tumors. It has been recommended by guidelines for diagnosis and treatment of hepatocellular carcinoma (HCC) as a curative treatment alongside surgical resection and liver transplantation. In recent years, with the continuous advancement and innovation of percutaneous ablation technologies, their clinical efficacy and safety have been significantly improved, which has led to the expanded application of percutaneous ablation in the treatment of HCC—more and more patients who were previously considered unsuitable for ablation therapies are now being treated with percutaneous ablation. Obviously, percutaneous ablation can reduce the risk of treatment changes from curative strategies to palliative strategies. Based on clinical practice experience, this review enumerates the advantages and disadvantages of different ablative modalities and summarizes the existing combinations of ablation techniques, thus will help clinicians choose the most appropriate ablative modality for each patient and will provide scientific guidance for improving prognosis and making evidence-based treatment decisions. In addition, we point out the challenges and future prospects of the ablation therapies, thereby providing direction for future research.

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“…RFA has been considered to be a safe and effective method for patients with CRLM [19]. However, several limitations to RFA, including increased impedance at 100 C, limited and small effective heating zones, reduced carbonization and multiple antenna limitations, constrain its wide clinical application [20,21].…”

Section: Introductionmentioning

confidence: 99%

Long-term outcome for colorectal liver metastases: combining hepatectomy with intraoperative ultrasound guided open microwave ablation versus hepatectomy alone

Dai

Yuan

et al. 2021

International Journal of Hyperthermia

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Objective: To compare the long-term outcome of combining hepatectomy with intraoperative ultrasound (IOUS)-guided open microwave ablation (MWA) versus hepatectomy alone in patients with colorectal cancer liver metastases (CRLM). Method: A retrospective analysis of patients with CRLM who underwent hepatectomy alone (HT group; 380 patients) or hepatectomy combined with IOUS-guided open MWA (HT þ MWA group; 57 patients) from April 2002 to September 2018 was conducted at our center. A propensity scorematched (PSM) analysis was used to reduce data bias between the two groups. Results: The overall survival (OS) and disease-free survival (DFS) were not significantly different between the two groups after matching. Although intrahepatic recurrence was more frequent in the HT þ MWA group in both the whole and matched cohort, the two groups exhibited similar rates of extrahepatic recurrence as well as concomitant intra-and extrahepatic recurrence. A higher number of CRLM (>3), larger maximum-size and absence of response to induction chemotherapy were independent risk factors for OS. Conclusion: The oncological outcomes of hepatectomy combined with intraoperative open ablation was not significantly different to hepatectomy alone and should be considered as a safe and fair option for patients with difficultly resectable CRLM.

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A prognostic nomogram for colorectal cancer liver metastases after percutaneous thermal ablation

Abstract: Thermal ablation was an effective therapy for CRCLM. Moreover, the nomogram was effective and simple for CRCLM patients undergoing thermal ablation.

Cited by 18 publications

References 42 publications

Ten-Year Outcomes of Percutaneous Radiofrequency Ablation for Colorectal Cancer Liver Metastases in Perivascular vs. Non-Perivascular Locations: A Propensity-Score Matched Study

Ten-Year Outcomes of Percutaneous Radiofrequency Ablation for Colorectal Cancer Liver Metastases in Perivascular vs. Non-Perivascular Locations: A Propensity-Score Matched Study

Challenges Facing Percutaneous Ablation in the Treatment of Hepatocellular Carcinoma: Extension of Ablation Criteria

Long-term outcome for colorectal liver metastases: combining hepatectomy with intraoperative ultrasound guided open microwave ablation versus hepatectomy alone

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