A programmed-pressure system

Ultra sensitive sensor with enhanced dynamic range for high speed detection of multi-color fluorescence radiation

“…A number of extremely sensitive fluorescence detection techniques are available based on registering single photons (Papageorgas et al, 1999;Tiberg and Paulauskas, 1981;Evtyushenkov et al, 1982;Shelevoi, 1985) commonly referred to as the single photon detection (SPD) techniques. Because of their complexity and cost, in biomedical applications single photon detection techniques are mostly used for time resolved fluorescence spectroscopy or detection of single fluorescent molecules (Dovichi et al, 1984;Chen and Dovichi, 1996;Soper et al, 1992Soper et al, , 1993.…”

Highly sensitive single photon detection system for multi-lane DNA sequencer

“…A number of extremely sensitive fluorescence detection techniques are available based on registering single photons [17][18][19][20] commonly referred to as the single photon detection (SPD) techniques. Because of their complexity and cost, singlephoton detection techniques were mostly used for specialized scientific applications, such as time resolved fluorescence spectroscopy or detection of single fluorescent molecules [21][22][23][24].…”

Dynamic range of fluorescence detection and base‐calling accuracy in DNA sequencer based on single‐photon counting

“…A number of extremely sensitive fluorescence detection techniques are available based on registering singlephotons [17][18][19][20] commonly referred to as the singlephoton detection (SPD) techniques. Because of their complexity and cost, SPD techniques were mostly used for specialized scientific applications, such as timeresolved fluorescence spectroscopy or detection of single fluorescent molecules [21][22][23][24].…”