A prospective cohort study of the risk factors for new falls and fragility fractures in self-caring elderly patients aged 80 years and over

Zhou, Jian; Liu, Bo; Mingzhao, Qin; Liu, Jinping

doi:10.1186/s12877-021-02043-x

Cited by 20 publications

(16 citation statements)

References 29 publications

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“…However, inconsistent result observed in the correlation between walking speed and fragility fracture. From this research, walking speed has shown to have no direct correlation with fragility fractures (16). Instead, reduced outdoor activities, reduced walking speed and increased TUG result were more likely to cause a new fall, which increase fragility fracture among elderly.…”

Section: Discussionmentioning

confidence: 68%

“…A total of 12 studies were selected for this systematic review (Figure 1). Six studies were rated as good quality (16,18,(22)(23)(24)26) and another six rated as fair quality (17,(19)(20)(21)25,27).…”

Section: Flow Of Studies In the Reviewmentioning

confidence: 99%

“…Most of the studies were using different types of outcome measures for gait speed assessment. The measurement included GAITRite instrument (19), 6-meter distance walking test in four studies (16,18,21,23), normal and rapid pace gait speed test (20), 2.44-meter walking speed test ( 22) and 3-meter walking test (24).…”

Section: Gait Speedmentioning

confidence: 99%

“…In this review, a total of nine studies were measuring physical performance of the participants. One of the studies assessed the participants' ability to cope with their daily living activities using the Activity of Daily Living (ADL) scale (Barthel Index) (16). While another study using the Rapid Assessment of Physical Activity (RAPA) questionnaire to assess the participants' level of physical performance (17).…”

Section: Physical Performancementioning

confidence: 99%

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Risk Factors Associated With Fragility Fracture Among Older Adults With Fragility Fracture: A Systematic Review

Kahar¹,

Chua²,

Singh³

et al. 2022

MJMHS

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Aim: To investigate risk factors of fragility fractures among older people. Data Sources: The electronic databases employed were PubMed, Science Direct, and Google Scholar from 2016 to December 2021. Review Method: The methodological quality of the studies was assessed using the National Institutes of Health (NIH) Quality Assessment Tool for Observational Cohort and Cross-sectional study. Two independent reviewers screened total 147 articles. Results: Twelve studies were finally included in this review that consisted of 7 cross sectional, 2 longitudinal and 3 cohort studies. Six studies were of good quality and six were fair. Studies that were of good quality showed that physical performance, muscle strength, and falls due to balance impairment were associated with an increased of fragility fractures. While the results for sarcopenia status were uncertain. Conclusion: This review suggests that physical functional related factors were main contributors to the risk of fragility fracture among older people. Lack of research in this area warrants more studies to be carried out in the future.

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Section: Discussionmentioning

confidence: 68%

Section: Flow Of Studies In the Reviewmentioning

confidence: 99%

Section: Gait Speedmentioning

confidence: 99%

Section: Physical Performancementioning

confidence: 99%

See 2 more Smart Citations

Risk Factors Associated With Fragility Fracture Among Older Adults With Fragility Fracture: A Systematic Review

Kahar¹,

Chua²,

Singh³

et al. 2022

MJMHS

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“…In terms of performing ADL independently, the literature reports that high scores on the Barthel indices were negatively correlated with experiencing new falls (25). Similarly, experiencing a fall or its recurrence increases its prevalence in individuals with low BADL scores (26).…”

Section: Discussionmentioning

confidence: 99%

Risk of Falls and Associated Factors Among Older Colombian Adults: A Secondary Sabe Analysis

Díaz-Vidal

Tadger

Quino-Ávila

et al. 2022

Preprint

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Introduction: Falls among the elderly are involuntary events that have a negative impact on their health, necessitating identification of their risk. Objective: To determine which factors are associated with the risk of falling in older Colombian adults. Methods: This was a secondary analysis of the SABE-Colombia study of 18,049 older adults, where the risk of falling was determined using the Downton scale and its association was investigated with variables such as age, height, weight, weight loss, alcohol consumption (in days), years of tobacco use, calf circumference, Barthel Index, instrumental activities of daily living (IADL), signs and symptoms, fear of falling, and architectural barriers outside and inside the home. The Lasso method was used to perform multiple analyses on the selected variables. Results: Being independent in performing basic ADL, as measured by the Barthel Index [odds ratio (OR): 92%], the absence of dangers at home (OR: 98%), needing assistance for medication management (OR: 66%) and transportation (OR: 83%), having a weight above the average of 78.15 kg (OR: 99%), and fewer years as a smoker (OR: 99%) showed no positive association with the risk of falling. Conclusions: Age, back pain, calf circumference, difficulty sleeping, dizziness, fear of falling, needing assistance walking 400 m, shortness of breath while awake, and tiredness are the variables associated with the risk of falling.

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Confounding association between plasma HDL‐C levels and increased fracture risk: A correspondence

Abbasi,

Qaiser,

Hoda

et al. 2024

Health Science Reports

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BackgroundThis article explores the association between fractures, particularly in the elderly, and elevated plasma high‐density lipoprotein cholesterol (HDL‐C) levels. The study challenges the conventional idea of HDL‐C as “good cholesterol” by revealing its potential role as a risk factor for fractures. Factors contributing to fractures in the elderly, such as diminishing bone strength due to aging‐related tissue breakdown, are discussed. Sedentary lifestyles, low bone mineral density (BMD), and habits like smoking and alcohol consumption compound fracture susceptibility.Materials and MethodsThe study delves into mechanisms linking elevated HDL‐C to fractures, using data from the ASPREE‐Fracturesub‐study of the ASPREE trial involving Australian and American participants aged 65 and above.ResultsThe study showed that over a 4‐year period, elevated HDL‐C levels in healthy older people were linked to a 14% higher fracture risk. This revelation expands the understanding of fracture risk factors beyond the established norms.ConclusionThe article emphasizes the need to reconsider HDL‐C's traditional role as an indicator of cardiovascular health, particularly in light of medications like Statins and Anacetrapib that raise HDL‐C levels. It calls for further exploration into the relationship between HDL‐C, fractures at varying sites, and different age groups. Practical implications involve incorporating fracture risk associated with high HDL‐C into clinical considerations, alongside advocating lifestyle changes for optimal HDL‐C levels. In summary, this study prompts a reevaluation of HDL‐C's implications in clinical practice, demanding further investigation into the intricacies of this relationship.

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A prospective cohort study of the risk factors for new falls and fragility fractures in self-caring elderly patients aged 80 years and over

Cited by 20 publications

References 29 publications

Risk Factors Associated With Fragility Fracture Among Older Adults With Fragility Fracture: A Systematic Review

Risk Factors Associated With Fragility Fracture Among Older Adults With Fragility Fracture: A Systematic Review

Risk of Falls and Associated Factors Among Older Colombian Adults: A Secondary Sabe Analysis

Confounding association between plasma HDL‐C levels and increased fracture risk: A correspondence

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